MétaCan
Menu
Back to cohort
Record W4233448447 · doi:10.32920/ryerson.14654661.v1

Diamagnetic Manipulation of Cell-Encapsulating Droplets

2021· preprint· en· W4233448447 on OpenAlexaff
Stephanie Buryk-Iggers

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldEngineering
TopicElectrohydrodynamics and Fluid Dynamics
Canadian institutionsTrent UniversityToronto Metropolitan University
Fundersnot available
KeywordsMicrofluidicsSortingNanotechnologyPhase (matter)Materials scienceDigital microfluidicsDiamagnetismChemistryMagnetic fieldOptoelectronicsElectrowettingPhysicsComputer science

Abstract

fetched live from OpenAlex

In this thesis, a microfluidic method for label-free control of cell encapsulating droplets is developed using diamagnetic forces. To generate droplets in a microfluidic device, we use a symmetrical flow-focusing design, where two streams of a continuous phase shear a single stream of a droplet phase, resulting in droplet generation. First, it is shown that by adjusting only the droplet phase flow rate, precise control of empty droplets can be achieved. Human prostate cells are then introduced to the system and encapsulated by droplets. Control of the cell-encapsulated droplets and empty droplets is studied. It is shown that cell-encapsulated droplets and empty droplets deflect by different amounts when exposed to the magnetic field. By exploiting this difference, efficient sorting of empty droplets from cell-encapsulated droplets is achieved at a purity of 85% in a single pass. Following sorting, cells are analyzed and show 90% viability after a two-hour incubation period.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.179
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.190
Teacher spread0.184 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

Explore more

Same topicElectrohydrodynamics and Fluid DynamicsFrench-language works237,207