Effects of the Aqueous Extract of Oxalis Barrelieri on Some Murine Models of Acute Depression
Bibliographic record
Abstract
Here, we examined the effects of the aqueous extract of Oxalis barrelieri (O.barrelieri) using some animal models of depression.White mice Mus musculus Swiss of both sexes, two months old where used.30 minutes after intraperitoneal administration of O. barrelieri, distilled water (10 mL/Kg and fluoxetine (20 mg/kg), behavioral parameters were examined in the forced swimming test (FST), the tail suspension test (TST) and sugar preference test.Behavioral events including mobility were noted.In the FST, a significant increase (p˂0.01) in the immobility onset to 68.33 s and the significant reduction (p˂0.05) up to 33.90% of the immobility time with O. barrelieri at doses 200 and 400 mg/kg respectively were observed.In the TST, O. barrelieri significantly increased (p˂0.01) up to 78.6 s the immobility appearance and decreased the immobility time to 28.65% at dose 200 mg/kg.It was also noted a significant dose-dependent increase (p˂0.05), from 117, 145 and 277%, in sweet water consumption at day 5 with doses 100, 200 and 400 mg/kg respectively.These antidepressant effects, probably through monoamine mechanism would probably be due to the presence of flavonoids and saponins in the aqueous extract of O. barrelieri.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.002 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".