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Record W4234957664 · doi:10.1002/adaw.32196

Briefly Noted

2018· article· en· W4234957664 on OpenAlexaboutno aff

Bibliographic record

VenueAlcoholism & Drug Abuse Weekly · 2018
Typearticle
Languageen
FieldMedicine
TopicOpioid Use Disorder Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsHeroinConsumption (sociology)Quarter (Canadian coin)MedicineMedical prescriptionRand corporationPsychiatrySociologyNursingHistoryManagement

Abstract

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Providing supervised access to pharmaceutical heroin to people whose use continues after trying multiple traditional treatments has been successful in other countries and should be piloted and studied in the United States, according to a RAND Corporation study released Dec. 6. “Given the increasing number of deaths associated with fentanyl and successful use of heroin‐assisted treatment abroad, the U.S. should pilot and study this approach in some cities,” said Beau Kilmer, leader of the project and co‐director of the RAND Drug Policy Research Center. “This is not a silver bullet or first‐line treatment. But there is evidence that it helps stabilize the lives of some people who use heroin.” The RAND findings appear in five related RAND publications and are based on experiences in other countries, including Canada, where Vancouver has that country's only heroin prescription. To assess the effectiveness of heroin‐assisted treatment and supervised consumption sites, RAND researchers reviewed scientific evidence and talked to more than two dozen stakeholders in Canada, the Netherlands, Switzerland and the United Kingdom to learn about their experiences with the approaches. They also spoke to more than 150 people in New Hampshire and Ohio, two states hard hit by opioid overdoses. The researchers found the documentation supporting supervised injection sites to be less solid than that supporting medical‐grade heroin provision. “Persistence does not imply effectiveness, but it seems unlikely that supervised consumption sites — which were initially controversial in many places — would have such longevity if they had serious adverse consequences for their clients or communities,” Kilmer said. For example, supervised consumption sites currently supervise a very small proportion of all injection sessions even in cities where they are well‐established. “It may even be worth asking whether the benefits of supervised consumption sites depend on there being a physical brick‐and‐mortar site, which may become a lightning rod for opposition, or if the key is just that consumption is supervised and whether there are other ways to get more opioid consumption supervised,” said Jonathan P. Caulkins, a report co‐author and a professor of public policy at Carnegie Mellon University. Caulkins said it also is possible that supervised injection of hydromorphone — a prescription opioid medication — may achieve similar benefits as offering supervised injectable heroin for those with heroin use disorder, but with fewer regulatory barriers in the United States, where heroin is illegal. The report, Considering Heroin‐Assisted Treatment and Supervised Drug Consumption Sites in the United States , is available at www.rand.org . Funding for the study was provided by RAND Ventures, which is supported by gifts from RAND supporters and income from operations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.277
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.282
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2018
Admission routes1
Has abstractyes

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