MétaCan
Menu
Back to cohort
Record W4236054979 · doi:10.5489/cuaj.715

Systematic review of therapy for neurogenic detrusor overactivity

2013· article· en· W4236054979 on OpenAlexvenueno aff
Clare J. Fowler

Bibliographic record

VenueCanadian Urological Association Journal · 2013
Typearticle
Languageen
FieldMedicine
TopicUrinary Bladder and Prostate Research
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineSpinal cord injuryPharmacotherapyAdverse effectMultiple sclerosisBotulinum toxinSpinal cordUrologyIntensive care medicineInternal medicineAnesthesiaPsychiatry

Abstract

fetched live from OpenAlex

While many neurologic diseases predispose patients to neurogenicdetrusor overactivity (NDO), the only populations that have beensystematically studied are adults with multiple sclerosis (MS), adultswith spinal cord injury (SCI) and children and young adults withmyelodysplasia. First-line pharmacotherapy for NDO is an antimuscarinicdrug. However, the evidence base for these agents inthis indication is poor. There is some high-quality evidence for theefficacy of detrusor injections of botulinum toxin A in the treatmentof NDO, with significant reduction in urgency incontinence episodes,improved urodynamic parameters, and improved quality oflife. While few adverse events have been reported with this therapy,there is a need for intermittent self-catheterization in these groups.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.017
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.997
Threshold uncertainty score0.032

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.017
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0070.005
Bibliometrics0.0060.007
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0020.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0100.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.289
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designSystematic review
DomainMethods
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2013
Admission routes1
Has abstractyes

Explore more

Same venueCanadian Urological Association JournalSame topicUrinary Bladder and Prostate ResearchFrench-language works237,207