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P69 Functionality, reliability, and performance of an accessorized pre-filled syringe with home-administered subcutaneous benralizumab for adult patients with severe asthma

2017· article· en· W4236950307 on OpenAlexaff
Antônio de Pádua Mansur, Gary T. Ferguson, Joseph B. Jacobs, Jean‐Louis Hébert, Corbin Clawson, Wu Tao, Yanping Wu, Matthew Goldman

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicPharmaceutical studies and practices
Canadian institutionsNanoQuébec (Canada)Institut de Recherche et de Développement en Agroenvironnement
Fundersnot available
KeywordsShireMedicineAdvisory committeeFamily medicineManagement

Abstract

fetched live from OpenAlex

AH Mansur: Received speaker fees and payment (including gifts or other consideration or ‘in kind’ compensation) through attending advisory board meeting to various companies including Novatis, Roche, AstraZeneca, NAPP, BI; Received educational grants for service development from Novartis pharmaceuticals; Participated in Phase IIb and III clinical trials with AstraZeneca, Novartis, Roche GT Ferguson: Received consultancy fees from AstraZeneca, Boehringer Ingelheim, and Pearl Therapeutics; Served on board or advisory committee for AstraZeneca, Pearl Therapeutics, and Novartis; Received research support from AstraZeneca, Boehringer Ingelheim, Pearl Therapeutics, Sunovion, Novartis, and Theravance JS Jacobs: Speaker/Teacher for Shire, Teva; Clinical Investigator for CSL Behring, Genentech, Regeneron, Sanofi, Shire, and Teva; Acted on Advisory committee for CSL Behring, Pharming Group, and Regeneron; Served as Independent Contractor for Genentech, CSL Behring, Regeneron, and Teva J Hebert: Consultant: Novartis, Merck, Teva, CSL Behring, Baxter, Shire; Conference Speaker: Merck, Novartis, Shire, Meda, CSL Behring; Investigator in clinical trials: Merck, Novartis, Stallergenis, GSK, Boehringer Ingelheim, CSL Behring, DBV C Clawson: Employee of MedImmune; Holds stock in AstraZeneca W Tao: Employee of AstraZeneca Y Wu: Employee of AstraZeneca M Goldman: Employee of AstraZeneca

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.008
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0060.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.329
Teacher spread0.296 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2017
Admission routes1
Has abstractyes

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