A Clinical Case Study of a 45 y/o Female Suffering with PTSD, Bipolar D/O, Depression, Anxiety and Chronic Pain Syndrome Taking 42-58 Pills Per Day and Weaned off of All Medications Using Medical Cannabis
Bibliographic record
Abstract
Post-traumatic stress disorder (PTSD) is a prevalent, chronic, and disabling depression and anxiety disorder that may develop following exposure to a traumatic event. Although the use of Medical Cannabis for the treatment of physical and psychological disorders is controversial, medical marijuana is currently legal in Canada, 33 states in the United States and many countries around the world. Studies published in Molecular Psychiatry and Science Daily showed that treatment using particular compounds found in cannabis may benefit those with PTSD, and that “plant-derived cannabinoids [psychoactive chemicals] such as cannabis may possess some benefits in individuals with PTSD by helping relieve haunting nightmares and other symptoms of PTSD” and as a result of taking medical cannabis, participants reported a decrease in re-experiencing the trauma, less avoidance of situations that reminded them of the trauma, and a decline in hyper-arousal, respectively. There’s also convincing evidence from multiple studies for reduced endocannabinoid availability in PTSD, i.e., reduced levels of the endocannabinoid anandamide and compensatory increase of CB1 receptor availability in PTSD, and an association between increased CB1 receptor availability in the amygdala and abnormal threat processing, as well as increased severity of hyperarousal, but not dysphoric symptomatology, in trauma survivors. Other studies suggest that Medical Cannabis therapy, as an adjunct to a traditional analgesic therapy, can be an efficacious tool to make more effective the management of chronic pain and its consequences on functional and psychological dimensions. The patient in this case study had been treated for over 20 years with multiple opiates, Selective Serotonin Re-Uptake Inhibitors (SSRIs), Serotonin Norepinephrine Re-Uptake Inhibitors (SNRIs), typical and atypical antipsychotics, antiepileptics, etc. to manage her multiple medical conditions, i.e., migraine headaches, seizures/tremors, general anxiety disorder with panic attacks, major depressive disorder-moderate and recurrent, attention deficit disorder, fibromyalgia, hot flashes and generalized edema. We will review how she was weaned off of the majority of the pharmacological treatments solely using Medical Cannabis in less than one year
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.031 | 0.013 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.003 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.002 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".