P01.01. Neural responses to the mechanical characteristics of a spinal manipulation: effect of varying segmental contact site
Bibliographic record
Abstract
In an anesthetized cat preparation, a simulated spinal manipulation [posterior-to-anterior; thrust amplitude = 21.3N (55% of an average cat’s body weight of 3.95 kg); thrust duration = 100ms] was delivered to the intact lower lumbar spine (L 6 – S 1) at each of 4 contact sites: L 6 spinous process, left L 6 mammillary process, left L 6 lamina, and L 7 spinous process. Electrophysiological recordings from individual muscle spindle afferents (n=16) innervating the L 6 multifidus and longissimus muscles were obtained from L 6 dorsal rootlets exposed through an L 5 laminectomy. Changes in neural activity during the manipulative thrust were compared between the four contact sites. All contact sites increased mean spindle activity: L 6 spinous: 85 impulses per second (imp/s) (60, 100; lower, upper 95% CI); L 6 lamina: 104 imp/s (79, 130); L 6 mammillary 80 imp/s (55, 105); and L 7 spinous 43 imp/s (18, 68). Lamina contact produced the largest increase, but only differences between the L 7 spinous and each L 6 contact site were statistically significant. The data suggest that maximizing sensory input from segmental paraspinal tissues during a spinal manipulation requires specifically contacting that segmental level. In addition, a lamina contact may most effectively create the dynamic mechanical stimulus that evokes the sensory input.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".