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Does Vaping Increase the Odds of Asthma?: A Canadian Community Health Survey Study

2021· article· en· W4240375110 on OpenAlexaffabout
Teresa To, K. Zhang, Emilie Terebessy, Ivy Fong, J. Zhu, Nicholas T. Vozoris, Cory Borkhoff, Theo J. Moraes, Chung‐Wai Chow, Robert Schwartz

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicSmoking Behavior and Cessation
Canadian institutionsUniversity of TorontoUniversity Health NetworkSt. Michael's HospitalHospital for Sick Children
Fundersnot available
KeywordsAsthmaMedicineOdds ratioBody mass indexPropensity score matchingConfoundingCommunity healthDemographyOddsLogistic regressionCross-sectional studyCohortConfidence intervalCohort studyEnvironmental healthPublic healthInternal medicine

Abstract

fetched live from OpenAlex

Rationale: While vaping is thought to be a safer alternative to smoking, emerging research suggests that e-cigarette (EC) use may have long-term health effects and may worsen pre-existing health conditions such as asthma. The objective of this study is to determine whether youth and young adults who are current EC users have increased odds of self-reported asthma and an asthma attack in the last 12 months. Methods: A cross-sectional study was conducted using the 2015-16 and 2017-18 cycles of the Canadian Community Health Survey (CCHS). The CCHS is a cross-sectional survey that collects self-reported information about health status, health determinants, and behaviours. The study cohort included all Canadians aged 12 years and over who participated in the CCHS. A propensity score method was used to identify five matched controls to individuals with self-reported EC use. Individuals were matched by CCHS cycle, age, sex, province of residence, local health unit, body mass index (BMI), household income, education, mental health, smoking history, and life stress. Odds ratios and 95% confidence intervals (CI) with asthma as the outcome and EC use as the exposure were determined using matched logistic regression, adjusting for potential confounding variables including those used for the propensity score matching. Modelling by smoking subgroup was also conducted. Results: The study cohort included 17,190 matched individuals from 222,949 CCHS respondents. 16.7% reported EC use in the past 30 days. Univariate analysis found an odds ratio of 1.19 (95% CI: 1.05-1.34) between EC use and self-reported asthma. Adjusting for potential confounders, individuals with EC use had 19% higher odds of having asthma (95% CI: 1.05-1.35). Current and former smokers had 20% (95% CI: 1.02-1.41) and 33% (95% CI: 1.05-1.69) higher odds of having asthma, respectively, while never smokers did not have significant associations, adjusted for potential confounders. Among those with asthma, EC users had 29% (95% CI: 1.02-1.63) higher odds of having an asthma attack in the last 12 months, adjusted for potential confounders. Conclusions: Current EC use is associated with significantly increased odds of having asthma, that is comparable to current smokers. These findings suggest that EC use is a modifiable risk factor for asthma to be considered in the primary care of youth and young adults. Figure Adjusted odds ratios of self-reported asthma from matched multivariable logistic regression for selected variables. Odds ratios adjusted for age, sex, province, BMI, household income, education, mental health, smoking history, and life stress.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.013
Threshold uncertainty score0.089

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.008
Science and technology studies0.0030.001
Scholarly communication0.0010.001
Open science0.0020.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.069
GPT teacher head0.354
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes2
Has abstractyes

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