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Record W4241837508 · doi:10.4161/cib.15440

Sleep homeostasis: Progress at a snail’s pace

2011· article· en· W4241837508 on OpenAlex
Richard Stephenson

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCommunicative & Integrative Biology · 2011
Typearticle
Languageen
FieldNeuroscience
TopicCircadian rhythm and melatonin
Canadian institutionsEsri (Canada)
Fundersnot available
KeywordsLymnaea stagnalisBiologyWakefulnessSnailNeuroscienceCircadian rhythmSleep (system call)Homeostatic plasticityHomeostasisEvolutionary biologyCell biologyEcologyGeneticsElectroencephalographyComputer scienceLong-term potentiationMetaplasticity

Abstract

fetched live from OpenAlex

We recently reported that a gastropod mollusc, Lymnaea stagnalis, exhibits a sleep-like quiescent state. However quiescence differed from mammalian sleep in that both circadian and homeostatic regulation seemed to be absent in the snail. In the present paper I explore the possibility that the clustered pattern of quiescence observed in the snail may provide insight into underlying regulatory mechanisms. Specifically, I hypothesize that clustering of quiescence arises from feedback modulation of a stochastic wake-quiescence oscillator. The feedback loop is postulated to limit cumulative wakefulness and to exert probabilistic modulation of wake duration. Computer simulations using this model succeeded in simulating snail wake-quiescence behaviour, confirming the plausibility of the hypothesis. Implications of this analysis for our understanding of mechanisms and evolution of sleep homeostasis are discussed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.840
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.003
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.086
GPT teacher head0.318
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it