MétaCan
Menu
Back to cohort
Record W4242135703 · doi:10.1158/1055-9965.epi-06-1036

Antibiotics and Breast Cancer

2007· article· en· W4242135703 on OpenAlexaboutno aff
F. William Danby

Bibliographic record

VenueCancer Epidemiology Biomarkers & Prevention · 2007
Typearticle
Languageen
FieldMedicine
TopicAcne and Rosacea Treatments and Effects
Canadian institutionsnot available
Fundersnot available
KeywordsAntibioticsBreast cancerCancerMedicineIntensive care medicineOncologyInternal medicineMicrobiologyBiology

Abstract

fetched live from OpenAlex

To the Editors: Drs. Friedman, Oestreicher, Chan and their associates, in reviewing the possible link between antibiotics and breast cancer, have noted their “review suggested that acne and/or rosacea could be the underlying factor” linking the two disorders (1).At a recent Harvard and McGill–sponsored symposium entitled “Milk, Hormones and Human Health,” the link between hormones in milk and the triad of acne vulgaris, breast cancer, and prostate cancer (all hormone-responsive tissues) was seen to be gradually strengthening.11Pollak M. Milk, hormones, and human health. Oct 23-25, 2006, Boston, Massachusetts. Proceedings of the Workshop. In preparation. With this as background, it is noted that although “hormone use was taken into account” in this study, the hormones present in dairy products consumed were not part of that assessment. This is understandable, with the recent link in the dermatology literature between acne and dairy consumption having been only recently published (2-4).Whereas no data have yet been published to link acne rosacea and dairy, the subject is being actively considered and Friedman et al. provide data from the first large population to suggest this intriguing possibility.Further work in this field must consider intake of dairy hormones as the most likely source of the “uncontrolled confounding” the authors cite. Indeed, what is seen as uncontrolled confounding by Friedman et al. may be, in effect, indirect confirmation of the postulated androgenic hormonal link between acne, breast cancer, and dairy product consumption.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.015
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.014
Threshold uncertainty score0.045

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.015
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0030.002
Science and technology studies0.0010.002
Scholarly communication0.0040.003
Open science0.0030.001
Research integrity0.0080.014
Insufficient payload (model declined to judge)0.0140.009

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.401
Teacher spread0.360 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2007
Admission routes1
Has abstractyes

Explore more

Same venueCancer Epidemiology Biomarkers & PreventionSame topicAcne and Rosacea Treatments and EffectsFrench-language works237,207