Surface-modified substrates for the Langmuir-Blodgett deposition of patterned ultra-thin and highly oriented collagen coatings
Bibliographic record
Abstract
As a pre-study for highly oriented collagen coatings on implants (with irregular surfaces and shapes), the Langmuir-Blodgett (LB) technology, a low-cost and straightforward approach, was pioneered. The effects of physicochemical (hydrophilic/hydrophobic) patterns and 3D-mechanical barriers present on substrate surfaces are studied in terms of the dynamics of collagen flow during LB film deposition and the formation of highly oriented coatings. Due to the large internal cohesion of collagen films, only large 3D-obstacles deflect the flow of collagen and lead to film rupture, suggesting that objects (screw-threaded dental implants) with small topographic features should be easily and evenly coatable. Moreover, hydrophilic/hydrophobic/collagen patterned substrate surfaces were fabricated, by partly removing coated collagen. These substrates are outstanding for timely studies that need identical conditions but different surface properties side by side. Crystallisation of barium oxalate was carried out as a proof-of-principle.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".