The Canadian Society of Animal Science Annual Conference, The Westin Ottawa, Ottawa, Ontario, Canada, 5–7 May 2015
Bibliographic record
Abstract
Liver abscesses are a prominent concern in cattle fed high-energy finishing rations.Challenges to the beef industry include impairment in productivity and loss of condemned organs.The increasing demand for enhanced productive performance in beef cattle with ensured food safety drives the need for complementary methods of monitoring health before slaughter.Our objective was to examine variation in biliary and blood plasma indicators of hepatic function to indirectly identify the presence or absence of liver abscesses.A total of 30 crossbred beef bulls (399 ± 29 d; 584 ± 128 kg at slaughter) were tested for productive performance.Samples of blood and bile collected at slaughter were evaluated for a panel of metabolites related to hepatic metabolism.The presence (n = 9) and absence (n = 21) of liver abscess served as criteria for classifying the bulls.Means comparisons between groups of bulls based on presence or absence of abscess were tested using the general linear model procedure in SAS.Plasma albumin was lower in bulls with abscess (32.11 g L -1 vs. 36.67g L -1 , P = 0.01).Thyroxine levels were also lower in plasma of the abscessed bulls (89.43 nmol L -1 vs. 101.52nmol L -1 , P = 0.02), as were blood plasma cholesterol levels (2.43 mmol L -1 vs. 3.08 mmol L -1 , P = 0.01).A retrospective analysis of blood parameters taken at eight occasions up to 34 d prior slaughter indicated lower blood plasma metabolites in bulls with abscessed livers, including glucose (4.66 mmol L -1 vs. 4.79 mmol L -1 , P = 0.03) and potassium (4.24 mmol L -1 vs. 4.49 mmol L -1 , P = 0.001); chloride was instead higher in the abscessed group (95.54 mmol L -1 vs. 94.43 mmol L -1 , P = 0.04).Carbon dioxide and urea were lower in abscessed bulls (22.19 mmol L -1 vs. 22.85 mmol L -1 , P = 0.005 and 3.69 mmol L -1 vs. 4.07 mmol L -1 , P < 0.01, respectively), as were levels of alkaline phosphatase (107.23 U L -1 vs. 123.26U L -1 , P < 0.01).Bulls with the presence or absence of liver abscess did not differ in age (395 ± 29 d vs. 400 ± 29 d, P = 0.63) or productive performance traits (i.e., feed efficiency, feed intake and average daily gain).Our results indicate that changes in hepatic function and intermediary metabolism accompanying liver abscesses can be represented by variations in corresponding blood plasma metabolites.Future work may be aimed at establishing profiles of healthy and diseased livers that may have application in the beef industry to ensure profitability and promote animal health.002-GS Storage characteristics, nutritive value and in vivo digestibility of large round bales of alfalfa hay treated with fibrolytic enzymes.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.005 | 0.003 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.003 | 0.002 |
| Science and technology studies | 0.005 | 0.002 |
| Scholarly communication | 0.005 | 0.001 |
| Open science | 0.002 | 0.003 |
| Research integrity | 0.002 | 0.002 |
| Insufficient payload (model declined to judge) | 0.194 | 0.053 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".