Bibliographic record
Abstract
It has been shown that extirpation of the thymus, the spleen, and the SAPP organs (appendix, sacculus rotundus and Peyer’s patches) in the normal adult rabbit does not affect the capacity of the rabbit to mount a humoral immune response to either particulate (SRBC or HRBC) or soluble protein (HSA or BGG or OA) antigens. Since it has previously been shown that the bone marrow does not constitute the organ capable of providing the host with the antibody-forming cells (AFC), it is concluded that no single lymphoid organ in the immunologically mature rabbit at the time of immunization constitutes the source of virgin AFC or serves as a necessary site of maturation of the AFC. Furthermore, the spleen, thymus and SAPP organs do not appear to possess any hormonal function with respect to the maintenance of immunocompetent cells. It is assumed that no single lymph node or the unorganized lymphoid cell accumulations or infiltrations would possess this unique role. It is, therefore, postulated that either all the lymphoid organs in the mature, adult rabbit possess virgin AFC or that the AFC represents a transient stage of morphological development of a potentially immunocompetent population of lymphocytes. Evidence has been presented that these cells, ontogenetically, probably arise in the gut-associated (SAPP) lymphoid organs and disseminate and infiltrate the other lymphoid organs either prenatally or in the early postnatal period.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.006 | 0.004 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".