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Improved thermotolerance in transgenic barley by overexpressing a heat shock factor gene (TaHsfA6b) from wheat

2020· dataset· en· W4249356475 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAuthorea · 2020
Typedataset
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicHeat shock proteins research
Canadian institutionsUniversité du Québec à Trois-Rivières
Fundersnot available
KeywordsHeat shock proteinHeat shock factorBiologyGeneTransgeneHeat shockCell biologyAbiotic stressGenetically modified cropsGene expressionDownregulation and upregulationAbiotic componentTranscription factorHsp70Genetics

Abstract

fetched live from OpenAlex

Temperature is one of the most important abiotic factors defining the yield potential of temperate cereal crops such as barley. The regulators of heat shock response (HSR); Heat shock factors (HSFs) modulate the transcription level of heat responsive genes in order to protect the plants against heat stress. In the present study, a heat shock factor from wheat (TaHSFA6b) is overexpressed in barley for providing thermotolerance. Transgenic barley lines overexpressing TaHSFA6b showed significant improvement in thermotolerance. The constitutive overexpression of TaHSFA6b gene upregulated the expression of major heat shock protein genes as well as other abiotic stress responsive genes. RNA-seq and qRT-PCR analysis showed upregulation of HSPs, chaperonins, DNAJ, LEA proteins and genes related to anti-oxidative enzymes in transgenic lines. Excessive generation and accumulation of ROS occurred in wild type plants during heat stress; however, the transgenic lines reflected improved ROS homeostasis mechanisms in the form of significantly low ROS accumulation under high temperature. There were no negative phenotypic changes in overexpression lines. The present study suggests that TaHSFA6b is one of the major regulators of HSR as it showed the capacity to alter the expression patterns of main defense related genes and enhance the thermotolerance of this cereal crops.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Dataset · Consensus signal: Dataset
Teacher disagreement score0.145
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.282
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it