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Record W4252193453 · doi:10.21203/rs.2.10463/v1

Clinical Outcome of Endovascular Coil Embolization For Cerebral Aneurysms In Asian Population In Relation To Risk Factors: A 3-Year Retrospective Analysis

2019· preprint· en· W4252193453 on OpenAlexaff
Saima Ahmad

Bibliographic record

VenueResearch Square · 2019
Typepreprint
Languageen
FieldMedicine
TopicIntracranial Aneurysms: Treatment and Complications
Canadian institutionsVictoria General Hospital
Fundersnot available
KeywordsMedicineModified Rankin ScaleComorbidityRetrospective cohort studyAneurysmPopulationSingle CenterStroke (engine)EmbolizationEndovascular coilingAdverse effectSurgeryPediatricsEndovascular treatmentInternal medicineIschemic stroke

Abstract

fetched live from OpenAlex

Abstract Background: This study reviews the impact of comorbidities on the success of endovascular coiling of both ruptured and unruptured intracranial aneurysms. Independent risk factors reviewed were age, sex, smoking and hypertension. Methods A 3-year retrospective analysis, performed to assess the clinical outcomes of patients with cerebral aneurysms treated endovascularly in Asian population. A total of 297 patients treated at a single center were included. Clinical outcomes were evaluated by regular follow-ups. A modified Rankin Scale was used to measure the clinical outcomes in patients. Results Study showed smoking had an adverse effect on clinical outcome, with smokers 35% less likely to recover, while hypertension played a minimal role with only 15%. It was found that aneurysms are more prevalent in women but women have a better chance of recovery. Men in their 20s and 30s have the best recovery, with comorbidities playing a negligible role. Similarly, patients who were above 40 had a lower chance of recovery compared to younger patients due to comorbidities irrespective of gender. Conclusions: Asian sub-continent has different genetic marker that lead to poorer outcomes of aneurysms in women, while outcomes are similar in men and women in developed nations. Smoking does not play a major role in women’s recovery. Men with comorbidity of smoking and hypertension were seen to be at higher risk and age played a major role in recovery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.076
GPT teacher head0.426
Teacher spread0.350 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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