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Record W4252611312 · doi:10.1017/s0317167100120086

25 Years ago in the Canadian Journal of Neurological Sciences

2000· article· en· W4252611312 on OpenAlexaffvenueabout
Frank Morrell, Noriko Tsuru, Thomas J. Hoeppner, David Morgan, Wilma Harrison

Bibliographic record

VenueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · 2000
Typearticle
Languageen
FieldNeuroscience
TopicNeurology and Historical Studies
Canadian institutionsVancouver Hospital and Health Sciences CentreUniversity of British Columbia
Fundersnot available
KeywordsAction (physics)NeuroscienceContent (measure theory)MedicineClinical neurologyPsychologyPhysicsMathematics

Abstract

fetched live from OpenAlex

Secondary epileptogenesis was induced in the hippocampal cortex of the paralyzed bullfrog by means of localized, unilateral, intermittent electrical stimulation (kindling). Stimuli were designed to yield a brief but definite afterdischarge. In control animals a progressive increase in after-discharge duration occurred at the 1 (stimulated) site and then at the 2 site (contralateral hippocampus). Spontaneous epileptiform potentials (SEPs) occurred between stimuli, eventually independently on both sides. Cycloheximide (50mg/kg) caused 88-99% reduction in protein synthesis, measured by l4 Cleucine incorporation into brain protein. Cycloheximide-treated animals revealed no evidence of progressive prolongation of after-discharge duration when subjected to the kindling procedure (p=0.1205x10 7 ). SEPs were reduced in the cycloheximide-treated animals, and confined to 1 hemisphere (p=0.6xl0 10 ).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.008
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies, Scholarly communication, Open science, Research integrity
Consensus categoriesScience and technology studies
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.449
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0100.008
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.004
Science and technology studies0.0070.024
Scholarly communication0.0010.001
Open science0.0070.000
Research integrity0.0000.004
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.058
GPT teacher head0.273
Teacher spread0.215 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2000
Admission routes3
Has abstractyes

Explore more

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