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Record W4253534330 · doi:10.1101/cshperspect.a018143

Microbial Speciation

2015· review· en· W4253534330 on OpenAlexafffund
B. Jesse Shapiro, Martin F. Polz

Bibliographic record

VenueCold Spring Harbor Perspectives in Biology · 2015
Typereview
Languageen
FieldEnvironmental Science
TopicMicrobial Community Ecology and Physiology
Canadian institutionsUniversité de Montréal
FundersNational Institute of Environmental Health SciencesScheme for Promotion of Academic and Research CollaborationCanada Research ChairsNatural Sciences and Engineering Research Council of CanadaBroad InstituteGordon and Betty Moore FoundationNational Science Foundation
KeywordsBiologyLibrary scienceEnvironmental ethicsPhilosophyComputer science

Abstract

fetched live from OpenAlex

What are species? How do they arise? These questions are not easy to answer and have been particularly controversial in microbiology. Yet, for those microbiologists studying environmental questions or dealing with clinical issues, the ability to name and recognize species, widely considered the fundamental units of ecology, can be practically useful. On a more fundamental level, the speciation problem, the focus here, is more mechanistic and conceptual. What is the origin of microbial species, and what evolutionary and ecological mechanisms keep them separate once they begin to diverge? To what extent are these mechanisms universal across diverse types of microbes, and more broadly across the entire the tree of life? Here, we propose that microbial speciation must be viewed in light of gene flow, which defines units of genetic similarity, and of natural selection, which defines units of phenotype and ecological function. We discuss to what extent ecological and genetic units overlap to form cohesive populations in the wild, based on recent evolutionary modeling and population genomics studies. These studies suggest a continuous "speciation spectrum," which microbial populations traverse in different ways depending on their balance of gene flow and natural selection.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.005
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0010.003
Scholarly communication0.0020.004
Open science0.0010.002
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0050.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.329
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations83
Published2015
Admission routes2
Has abstractyes

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