Education
Bibliographic record
Abstract
Background: Dermatofibrosarcoma protuberans (DFSP) is a dermal and subcutaneous intermediate tumour. Compared to other techniques, biopsy is not only a rapid outpatient procedure but also the optimal choice for unresectable patients with cutaneous tumor before neoadjuvant therapy. In DFSP, the rarity of tumours, atypical clinical manifestation and uncommon histological features may cause diagnosis pitfalls in the limited biopsy samples. The most remarkable cytogenetic characteristic of DFSP is the formation of the COL1A1-PDGFB fusion gene. The aim of this study was to analyse the clinical application value of fluorescence in situ hybridization (FISH) in biopsy of DFSP. Design: Twenty-three consecutive biopsy specimens of DFSP, collected from 2007 to 2014, were reviewed for clinicopathological features and immunohistochemical staining results, and detected with the COL1A1/PDGFB Fusion Probe and the PDGFB Break Apart Probe using FISH analysis.Controls included 5 fibromatosis and dermatofibromas. The positive criteria for COL1A1-PDGFB gene fusion and PDGFB rearrangement were both 10% and more of the cells showed meaningful signals.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".