Dynamic modelling, simulation and experiments of a micro-cutter with applications to cell perforation
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
The nonlinear three-dimensional dynamic equations of motion of a micro-cutter driven longitudinally at ultrasonic operating frequencies are derived using Kane's method. The micro-cutter is assumed to be immersed in a fluid, and in contact with an oocyte, which is to be perforated by the micro-cutter. The micro-cutter is modelled as an Euler-Bernoulli cantilever beam attached to a moving base. The shear and rotary inertia effects are neglected by considering a slender-shaped beam with homogeneous and isotropic material properties. It is assumed that there is no slip between the micro-cutter tip and the embryo membrane. The model presented demonstrates that the longitudinal excitation input of a micropipette results in excitation of out-of-plane, lateral motion due to the nonlinear dynamic coupling of the dynamics. Experimental results of membrane perforation are presented in the work supporting oocyte micro-cutter observations regarding suitable frequencies of excitation for effective oocyte membrane perforation.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it