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Record W4280580357 · doi:10.1038/s41591-022-01805-3

Empagliflozin add-on therapy to closed-loop insulin delivery in type 1 diabetes: a 2 × 2 factorial randomized crossover trial

2022· article· en· W4280580357 on OpenAlexafffund
Ahmad Haidar, Leif Erik Lovblom, Nancy Cardinez, Nikita Gouchie‐Provencher, Andrej Orszag, Michael A. Tsoukas, C. Marcelo Falappa, Adnan Jafar, Milad Ghanbari, Devrim Eldelekli, Joanna Rutkowski, Jean‐François Yale, Bruce A. Perkins

Bibliographic record

VenueNature Medicine · 2022
Typearticle
Languageen
FieldMedicine
TopicDiabetes Management and Research
Canadian institutionsUniversity of TorontoLunenfeld-Tanenbaum Research InstituteMount Sinai HospitalMcGill UniversitySinai Health SystemMcGill University Health Centre
FundersCanadian Institutes of Health ResearchUniversity of TorontoGovernment of CanadaJuvenile Diabetes Research Foundation United States of AmericaDiabetes Action Research and Education Foundation
KeywordsCrossover studyRandomized controlled trialType 2 diabetesMedicineEmpagliflozinClosed loopInsulinDiabetes mellitusInsulin deliveryInternal medicineType 1 diabetesEndocrinologyAlternative medicine

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.142
Threshold uncertainty score0.996

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.337
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations39
Published2022
Admission routes2
Has abstractno

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