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A Mini Review of Underutilized Native Plants from East Malaysia’s Rainforestsas Potential Hypertensive Drugs

2022· review· en· W4280643258 on OpenAlexaboutno aff
Fong Tyng Chee, Su Na Chin, Fui Fui Lem

Bibliographic record

VenueThe Natural Products Journal · 2022
Typereview
Languageen
FieldMedicine
TopicMedicinal Plants and Neuroprotection
Canadian institutionsnot available
Fundersnot available
KeywordsEthnomedicineIndigenousRainforestMedicinal plantsTraditional medicineEthnic groupMedicineNative plantGeographyBiologyIntroduced speciesEcologyPolitical science

Abstract

fetched live from OpenAlex

Abstract: Hypertension is a risk factor for cardiovascular diseases, which are on the rise throughout the world at an alarming rate. As a result, a variety of techniques to help in the prevention and control of hypertension have been tried, one of which is the use of natural medicines derived from medicinal plants. The relevance of plant-based medicine is now recognised by western countries, as seen by Canada's Natural Health Product Regulations, which were promulgated in January 2004. The Southeast Asian rainforests, notably in East Malaysia, are home to a diverse range of medicinal plant species with endless potential as pharmacological candidates, particularly as antihypertensive agents. The indigenous ethnic groups of East Malaysia have long utilised a broad variety of medicinal plant species to treat hypertension, thanks to their extensive usage of traditional remedies and in-depth understanding of ethnomedicine, which are fundamental elements of their culture. However, scientific understanding of ethnomedicines used to treat hypertension, particularly the processes underlying their antihypertensive action, is inadequate. Based on previous scientific studies, this review aims to address the antihypertensive effects of medicinal plants used by indigenous ethnic groups in East Malaysia, Sabah, in order to provide insights into the mechanisms of the plants' antihypertensive activity for the development of antihypertensive agents from these native plants.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.005
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.002
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.061
GPT teacher head0.318
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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