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Record W4281399880 · doi:10.1021/acs.organomet.2c00162

Synthesis, Characterization, and Reactivity of Low-Coordinate Titanium(III) Amido Complexes

2022· article· en· W4281399880 on OpenAlexfundno aff
Alejandro J. Cuellar De Lucio, Irene C. Cai, Ryan J. Witzke, Addison N. Desnoyer, T. Don Tilley

Bibliographic record

VenueOrganometallics · 2022
Typearticle
Languageen
FieldChemistry
TopicSynthetic Organic Chemistry Methods
Canadian institutionsnot available
FundersNatural Sciences and Engineering Research Council of CanadaUC Berkeley College of ChemistryUniversity of California BerkeleyOffice of ScienceNational Institutes of HealthNational Science Foundation
KeywordsChemistryAlkoxideAdductReactivity (psychology)MetathesisSalt metathesis reactionTitaniumLewis acids and basesSilylationNuclear magnetic resonance spectroscopyMedicinal chemistryAlkylationStereochemistryCatalysisOrganic chemistryPolymerization

Abstract

fetched live from OpenAlex

Low-coordinate titanium(III) amido complexes were readily prepared via treatment of β-TiCl3 with 1 or 2 equiv of Li[N(SiiPr3)DIPP] (DIPP = 2,6-di-iso-propylphenyl) to form dinuclear [{Ti(N(SiiPr3)DIPP)Cl(μ-Cl)}2] (1) or mononuclear Ti[N(SiiPr3)DIPP]2Cl (2), respectively. Both complexes were characterized by a variety of methods, including NMR spectroscopy, Evans method magnetic susceptibility, and single-crystal X-ray diffraction studies. Complex 1 was shown to be a versatile precursor for salt metathesis reactions to form heteroleptic complexes bearing alkoxide or silyl ligands. Alternatively, 1 formed adducts with Lewis bases such as 4-dimethylaminopyridine (DMAP) that are paramagnetic, mononuclear species. The base-stabilized complex 5 was alkylated with 1 or 2 equiv of LiCH2SiMe3 to form mono- or dialkyl products, respectively. In contrast, treatment of complex 1 in the absence of DMAP with 2 equiv of LiCH2SiMe3 results in the ultimate formation of a dinuclear cyclometalated complex 9 bearing a [Ti2(μ-Cl)2(μ:η1-CH2SiMe2CH2-)] core. This study demonstrates the convenient synthesis of a family of low-coordinate titanium(III) amido complexes possessing a variety of neutral and monoanionic ligands.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.016
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0130.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.233
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2022
Admission routes1
Has abstractyes

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