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RETRACTED: 2-methoxy-4-(((5-nitropyridin-2-yl)imino)methyl)phenol Schiff base ligand and its Cu(II) and Zn(II) complexes: synthesis, characterization and biological investigations

2022· article· en· 18 citations· W4281745464 on OpenAlex· 10.1016/j.heliyon.2022.e09648

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Abstract

In this current work we have prepared a Schiff base ligand, (HL) derived from 5- nitropyridine-2-amine with 4-hydroxy-3-methoxybenzaldehyde and its Cu(II), and Zn(II) in 2:1 stoichiometric ratio (2HL:M). The formation of the ligand and the metal complexes were evaluated by means of MS, FT-IR, UV-Visible, 1H-NMR, 13C-NMR and thermogravimetric methods. The free radical scavenging activity of compounds was evaluated through a sequence of in vitro assays viz., DPPH, ABTS and Superoxide where BHA was used as a positive controller. In vitro α-glucosidase inhibitory activities showed that complexes had considerable inhibitory potential when compared to the ligand.

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The record

Venue
Heliyon
Topic
Metal complexes synthesis and properties
Field
Medicine
Canadian institutions
Funders
Institute of Infection and Immunity
Keywords
Schiff baseChemistryLigand (biochemistry)PhenolThermogravimetric analysisABTSDPPHProton NMRStoichiometryCarbon-13 NMRAmine gas treatingMetalNuclear chemistryMedicinal chemistryPolymer chemistryStereochemistryOrganic chemistryAntioxidantBiochemistry
Has abstract in OpenAlex
yes