Editorial: RNA-Mediated Epigenetic and Transcriptional Regulation
Bibliographic record
Abstract
RNA plays major regulatory roles in many processes beyond transcription, including protein complex formation, maintenance of genomic stability, and establishment of higher-order cellular structures via phase separation. Accordingly, regulation of RNA abundance, processing, and modification can have a profound impact on cellular and organismal biology. In recent years, significant progress has been made to decipher the complex molecular details and functional interplay between RNA and regulatory processes have begun to emerge. These studies have shed light on how perturbation to these mechanisms can yield aberrant biology, including formation of disease states such as cancers. In this Research Topic "RNA-Mediated Epigenetic and Transcriptional Regulation," several articles highlight the importance of RNA-mediated regulation in different pathological contexts such as cancers and retinal degeneration, and developmental/adaptation processes such as sperm development, resistance to pathogens, and adaptation to cold. Altogether, this Research Topic further highlights the importance of RNA as an effector molecule in biology and underscores its biochemical versatility as a regulatory molecule.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".