MétaCan
Menu
Back to cohort
Record W4283789043 · doi:10.1093/cercor/bhac236

Optimal blocking of the cerebral cortex for cytoarchitectonic examination: a neuronavigation-based approach

2022· article· en· W4283789043 on OpenAlexafffund
Jennifer Novek, Trisanna Sprung‐Much, Erika Nolan, Michael Petrides

Bibliographic record

VenueCerebral Cortex · 2022
Typearticle
Languageen
FieldMedicine
TopicAdvanced Neuroimaging Techniques and Applications
Canadian institutionsMcGill UniversityMontreal Neurological Institute and Hospital
FundersCanadian Institutes of Health ResearchHuman Frontier Science Program
KeywordsCytoarchitectureSulcusCortex (anatomy)Central sulcusAnatomyCerebral cortexNeuroscienceCoronal planeSomatosensory systemNeuroanatomyBiologyMotor cortex

Abstract

fetched live from OpenAlex

Certain sulci of the human cerebral cortex hold consistent relationships to cytoarchitectonic areas (e.g. the primary motor cortical area 4 and the somatosensory cortical area 3 occupy the anterior and posterior banks of the central sulcus, respectively). Recent research has improved knowledge of the cortical sulci and their variability across individuals. However, other than the so-called primary sulci, understanding of the precise relationships cortical folds hold with many cytoarchitectonic areas remains elusive. To examine these relationships, the cortex must be blocked, sectioned, and histologically processed in a manner that allows the cytoarchitectonic layers to be clearly observed. The optimal strategy to view the cytoarchitecture is to block and section the cortex perpendicular to the sulcal orientation. Most cytoarchitectonic investigations of the cortex, however, have been conducted on specimens cut along a single axis (e.g. the coronal plane), which distorts the appearance of the cytoarchitectonic layers within parts of the cortical ribbon not sectioned optimally. Thus, to understand further the relationships between sulci and cytoarchitectonic areas, the cortex should be sectioned optimally to the sulci of interest. A novel approach for blocking the cortex optimally using structural magnetic resonance imaging (MRI) and surgical neuronavigation tools is presented here.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.330
Threshold uncertainty score0.570

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.051
GPT teacher head0.313
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2022
Admission routes2
Has abstractyes

Explore more

Same venueCerebral CortexSame topicAdvanced Neuroimaging Techniques and ApplicationsFrench-language works237,207