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Record W4285090825 · doi:10.1101/2022.07.11.22277498

Assessment of concordance between related systematic reviews and between related guideline recommendations: protocol for a methodological survey

2022· preprint· en· W4285090825 on OpenAlexaff
Arnav Agarwal, Loai Albarqouni, Nour Badran, Nina Brax, Pooja Gandhi, Tiago Pereira, A K Roberts, Ola El Zein, Elie A. Akl

Bibliographic record

VenuemedRxiv · 2022
Typepreprint
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsUniversity of OttawaSt. Michael's HospitalToronto Rehabilitation InstituteUniversity Health NetworkUniversity of TorontoMcMaster UniversityImpact
Fundersnot available
KeywordsConcordanceGuidelineProtocol (science)Systematic reviewClinical PracticeMedicineMEDLINEPsychologyManagement scienceFamily medicineAlternative medicinePathologyPolitical scienceEngineering

Abstract

fetched live from OpenAlex

Abstract Independent systematic reviewers may arrive at different conclusions when analyzing evidence addressing the same clinical questions. Similarly, independent expert panels may arrive at different recommendations addressing the same clinical topics. When faced with a multiplicity of reviews or guidelines on a given topic, users are likely to benefit from a structured approach to evaluate concordance, and to explain discordant findings and recommendations. This protocol proposes a methodological survey to evaluate the prevalence of concordance between reviews addressing similar clinical questions, and between clinical practice guidelines addressing similar topics; and to identify methodological frameworks for the evaluation of concordance between related reviews and between related guidelines.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmaMetaresearch
Domain: Evaluation · Genre: Protocol
About the Canadian research system: no · About a Canadian topic: no
Observationallow
gptMetaresearchMeta-epidemiology (broad)
Domain: Methods · Genre: Protocol
About the Canadian research system: no · About a Canadian topic: no
Systematic reviewmedium
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.660
metaresearch head score (Gemma)0.334
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Meta-epidemiology (broad), Insufficient payload (model declined to judge)
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.327
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.6600.334
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0190.003
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0040.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0070.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.929
GPT teacher head0.673
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

MetaresearchMeta-epidemiology (broad)

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designObservational · Systematic review
DomainEvaluation · Methods
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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