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Record W4285590588 · doi:10.26434/chemrxiv-2022-wcjjj

Multi-element compound specific isotope analysis reveals aerobic biodegradation of 2,3-dichloroaniline at a complex site

2022· preprint· en· W4285590588 on OpenAlexafffund
Shamsunnahar Suchana, Sofia Pimentel Araujo, Line Lomheim, Elizabeth A. Edwards, E. Erin Mack, Elodie Passeport

Bibliographic record

VenueChemRxiv · 2022
Typepreprint
Languageen
FieldEnvironmental Science
TopicWater Treatment and Disinfection
Canadian institutionsUniversity of Toronto
FundersNatural Sciences and Engineering Research Council of CanadaUniversity of Toronto
KeywordsEnvironmental chemistryIsotope analysisBiodegradationChemistryBiotransformationIsotope fractionationBioremediationIsotopes of carbonGroundwaterIsotopes of nitrogenContaminationFractionationNitrogenTotal organic carbonEcologyChromatographyOrganic chemistryGeologyBiology

Abstract

fetched live from OpenAlex

Compound specific isotope analysis (CSIA) is an established tool for evaluating in situ transformation of organic contaminants. To date, CSIA has never been applied to understand the in situ fate of 2,3-dichloroaniline (2,3-DCA). Although persistent in the environment, several microorganisms were identified as able to degrade 2,3-DCA, thus making this contaminant a potential candidate for bioremediation. Using a controlled-laboratory experiment, we determined, for the first time, negligible carbon and hydrogen isotope fractionation, and a significant inverse nitrogen isotope effect during aerobic 2,3-DCA biodegradation via dioxygenation using a mixed enrichment culture. The corresponding AKIEN values ranged from 0.9938±0.0003 to 0.9922±0.0004. The ε_(N,bulk) values, ranging from +6.2±0.3 to +7.9±0.4‰ was applied to investigate the potential in situ 2,3-DCA biotransformation at a contaminated site, where the field-obtained carbon and nitrogen isotope signatures suggested aerobic biotransformation by native microorganisms. Under the assumption of the applicability of the Rayleigh model at the field site, the extent of 2,3-DCA transformation was estimated at up to 80 to 90%. This study proposes multi-element CSIA of 2,3-DCA as a novel application to study 2,3-DCA fate in groundwater and surface water.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.267
Teacher spread0.221 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes2
Has abstractyes

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