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Record W4285665437 · doi:10.34883/pi.2020.12.3.005

Analysis of Preoperative Status of High-Risk Patients Admitted for Surgical Myocardial Revascularization

2020· article· ru· W4285665437 on OpenAlexaboutno aff
Е.К. Гогаева, В. В. Лазоришинець, А.В. Руденко, Л.С. Дзахоева

Bibliographic record

VenueКардиология в Беларуси · 2020
Typearticle
Languageru
FieldMedicine
TopicCardiac, Anesthesia and Surgical Outcomes
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineInternal medicineCardiologyEuroSCORECanadian Cardiovascular SocietyUnstable anginaRevascularizationAnginaVentricleCoronary artery diseaseIschemic cardiomyopathyMyocardial infarctionCardiac surgerySurgeryEjection fractionHeart failure

Abstract

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Введение. Ежегодно увеличивается количество операций реваскуляризации миокарда у пациентов высокого риска. C 2011 г. для стратификации риска в кардиохирургии используется шкала EuroScore II, согласно которой к группе высокого риска относятся пациенты с прогнозируемой вероятностью летального исхода более 5%.Цель. Проанализировать дооперационный статус пациентов высокого риска, госпитализированных для проведения хирургической реваскуляризации.Материалы и методы. 575 пациентов высокого риска, госпитализированных в институт для выполнения хирургической реваскуляризиции (среди которых мужчин 561 – 97,5%; средний возраст 62±32 года). Всем пациентам были выполнены общеклинические исследования: ЭКГ, ЭхоКГ, коронаровентрикулография с последующей хирургической реваскуляризацией.Результаты и обсуждение. При ретроспективном анализе исходных данных пациентов стабильная форма ишемической болезни сердца отмечалась у 224 (38,9%) пациентов, нестабильная стенокардия у 183 (31,8%) пациентов, острый трансмуральный инфаркт миокарда на момент госпитализации был у 8 (1,39%) пациентов. Также диагностированы осложненные формы ИБС: аневризма левого желудочка выявлена у 17 (2,95%) пациентов, ишемическая кардиомиопатия у 132 (22,9%) пациентов, ишемическая митральная недостаточность в 7 (1,21%) случаях. Сочетание ИБС с аортальным стенозом имело место у 4 (0,7%) пациентов. При анализе сопутствующих заболеваний выявили: артериальную гипертензию (АГ) у 566 (98,4%) пациентов, сахарный диабет (СД) у 125 (21,7%) пациентов, острое нарушение мозгового кровообращения (ОНМК) в анамнезе перенесли 69 (12%) пациентов, хроническую почечную недостаточность имели 111 (19,3%) пациентов, хроническое обструктивное заболевание легких (ХОЗЛ) – 165 (28,6%) пациентов, подагрой страдали 27 (4,69%) пациентов, дисциркуляторная энцефалопатия (ДЭП) диагностирована у 429 (74,6%) пациентов, вестибуло-атактические нарушения выявлены у 276 (48%) пациентов. Средний ES II исследуемой группы составлял 9,2%. Индивидуальный подход в лечебно-диагностическом процессе позволил выписать всех пациентов из института после успешно проведенной хирургической реваскуляризации миокарда.Выводы. Анализ дооперационного статуса пациентов позволяет выявить кардиальные и некардиальные факторы, на основании которых стратифицируется риск по шкале ES II. Для пациентов высокого риска важна медикаментозная компенсация сопутствующих заболеваний на дооперационном этапе. Introduction. Annually we observe the increase of the quantity of high-risk patients in cardiac surgery. Nowadays, risk stratification is carried out on the EuroScore II scale, where the high-risk patients have ES II >5%.Purpose. To analyze the preoperative status of high-risk patients with ischemic heart disease (IHD) admitted for surgical revascularization.Materials and methods. 575 high-risk patients (pts) admitted for coronary revascularization (male group – 561 (97.5%) patients at the average age of 62+23 y.o.). In all patients, we performed ECG, ECHO, coronary angiography, and coronary revascularization.Results and discussion. In retrospective analysis of preoperative data, we found the following: stable angina pectoris was observed in 224 (38.9%) patients, unstable angina pectoris – 183 (31.8%) patients, acute Q-MI – 8 (1.39%) patients. Complicated forms of IHD were diagnosed in 156 patients, among which 17 (2.95%) patients had aneurysm of the left ventricle (LV), 132 (22.9%) patients had ischemic cardiomyopathy, 7 (1.2%) patients had ischemic mitral insufficiency. Combination of IHD with aortic stenosis was observed in 4 (0.7%) patients. Analysis of comorbidity showed that arterial hypertension was observed in 566 (98.4%) patients, diabetes mellitus – in 125 (21.7%) patients, stroke in anamnesis – in 69 (12%) patients, gout – in 27 (4.69%) patients, encephalopathy – in 429 (74.6%) patients, and vestibulo-ataxic disorders – in 276 (48%) patients. Cardiac procedures in anamnesis were revealed in 96 (16.7%) patients, in which there were: 7 (7.2%) patients after CABG, 80 (13.9%) patients after stenting of coronary arteries, 7 (7.2%) patients had angioplasty of CA, and 2 (2.08%) patients had pacemaker. Atrial fibrillation (AF) was observed in 62 (10.7%) patients; at the time of hospitalization, AF was observed in 23 (4%) patients. Average ES II was 9.7%; all patients were discharged from the Institute after surgical revascularization and correction of concomitant pathology of the valves and left ventricle.Conclusions. Evaluation of preoperative status of patients lets to identify the cardiac and non- cardiac factors for risk stratification. At the time of hospitalization for surgical treatment of high- risk patients, it is also important to compensate the concomitant diseases (diabetes mellitus, neurological dysfunction etc.).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.260
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Published2020
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