Sensitivity of the Cervical Disc Loads, Translations, Intradiscal Pressure, and Muscle Activity Due to Segmental Mass, Disc Stiffness, and Muscle Strength in an Upright Neutral Posture
Bibliographic record
Abstract
Musculoskeletal disorders of the cervical spine have increased considerably in recent times. To understand the effects of various biomechanical factors, quantifying the differences in disc loads, motion, and muscle force/activity is necessary. The kinematic, kinetic, or muscle response may vary in a neutral posture due to interindividual differences in segmental mass, cervical disc stiffness, and muscle strength. Therefore, our study aimed to develop an inverse dynamic model of the cervical spine, estimate the differences in disc loads, translations, intradiscal pressure, and muscle force/activity in a neutral posture and compare these results with data available in the literature. A head–neck complex with nine segments (head, C1–T1) was developed with joints having three rotational and three translational degrees of freedom, 517 nonlinear ligament fibers, and 258 muscle fascicles. A sensitivity analysis was performed to calculate the effect of segmental mass (5th to 95th percentile), translational disc stiffness (0.5–1.5), and muscle strength (0.5–1.5) on the cervical disc loads (C2–C3 to C7–T1), disc translations, intradiscal pressure, and muscle force/activity in a neutral posture. In addition, two axial external load conditions (0 and 40 N) were also considered on the head. The estimated intradiscal pressures (0.2–0.56 MPa) at 0 N axial load were comparable to in vivo measurements found in the literature, whereas at 40 N, the values were 0.39–0.93 MPa. With increased segmental mass (5th to 95th), the disc loads, translations, and muscle forces/activities increased to 69% at 0 N and 34% at 40 N axial load. With increased disc stiffness (0.5–1.5), the maximum differences in axial (<1%) and shear loads (4%) were trivial; however, the translations were reduced by 67%, whereas the differences in individual muscle group forces/activities varied largely. With increased muscle strength (0.5–1.5), the muscle activity decreased by 200%. For 40 vs. 0 N, the differences in disc loads, translations, and muscle forces/activities were in the range of 52–129%. Significant differences were estimated in disc loads, translations, and muscle force/activity in the normal population, which could help distinguish between normal and pathological cervical spine conditions.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".