Case report of an angiosarcoma of the abdominal wall during liraglutide injections
Bibliographic record
Abstract
ABSTRACT Introduction: Angiosarcoma is a very rare but highly aggressive malignant vascular tumor. Sporadic cases that develop in the abdominal wall are almost exclusively observed in obese patients. The underlying causes remain unclear. Liraglutide, a glucagon-like peptid-1 agonist receptor treatment, effective for weight management and glycemic control in type 2 diabetes, is not known to be associated with the occurrence of angiosarcoma. Case presentation: A 62-year-old woman developed a very aggressive, rapidly recurrent angiosarcoma of the abdominal wall. The angiosarcoma developed while she was taking liraglutide injections. The patient died within few months. Discussion: Angiosarcoma, particularly of the abdominal wall, is very rare, and occurs mainly in obese patients. This cancer had a highly aggressive behavior. The association with liraglutide and angiosarcoma cannot be established nor eliminated from this case and literature review. Conclusion: Angiosarcoma is a rare and highly aggressive cancer that occasionally originates in the abdominal wall. In this case, in addition to the underlying obesity, a possible association of her liraglutide subcutaneous injections cannot be excluded. In the future, if other cases of abdominal walls angiosarcomas associated with liraglutide subcutaneous injections were to be reported, a possible causality should be further investigated. Highlights
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".