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Record W4286791354 · doi:10.5281/zenodo.5585278

Preprint: Selection of high-trait emotivity affects the volume of sensory and emotional-related brain regions in male Japanese quails

2021· preprint· en· W4286791354 on OpenAlexaff
Marine Siwiaszczyk, Mélody Morisse, Ludovic Calandreau, David André Barrière, Justine Beaujoin, Baptiste Mulot, Frédéric Andersson, Cyril Poupon, Scott Love, Élodie Chaillou

Bibliographic record

VenueHAL (Le Centre pour la Communication Scientifique Directe) · 2021
Typepreprint
Languageen
FieldAgricultural and Biological Sciences
TopicAnimal Nutrition and Physiology
Canadian institutionsUniversity of FrederictonCentre Hospitalier Universitaire Sainte-Justine
FundersEuropean Commission
KeywordsTraitSelection (genetic algorithm)Brain sizeSensory systemVolume (thermodynamics)PsychologyBiologyCognitive psychologyArtificial intelligenceComputer scienceMedicine

Abstract

fetched live from OpenAlex

Abstract Japanese quails (Coturnix japonica) divergently selected based on their behavior during a tonic immobility test are an excellent model to study the link between brain morphology and behavior expression. The LTI (Long Tonic Immobility) and STI (Short Tonic Immobility) quail lines differ in their level of emotivity, with LTI quails being selected for their high-trait emotivity. Here, comparing the brain regions of the LTI and STI lines of male Japanese quails, we test the hypothesis that this divergent selection could have influenced brain anatomy, in particular, those regions involved in sensory and emotional processing. The heads of twenty, 10 weeks old male Japanese quails (10 STI and 10 LTI) were imaged ex-vivo using ultra high-resolution (11.7 Tesla) magnetic resonance imaging. The resulting images were used to create a population-averaged quail brain template and manually segmented 3D whole-brain atlas (openly available: https://doi.org/10.5281/zenodo.4700522). The atlas is composed of 191 brain regions, the ventricular system, pineal and pituitary glands. Thanks to this atlas, an exploratory analysis was conducted to compare brain regions between the two lines: the relative volumes of 33 regions were impacted (with 24 larger relative volumes being found in STI). This demonstrates for the first time in male Japanese quail that genetic selection for a specific emotional behavior (tonic immobility) modifies the anatomy of brain regions involved in sensory and emotional processing.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.211
Teacher spread0.197 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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