Comparison of Effect of Aloe vera Gel and Nystatin on Candida Species: An In Vitro Study
Bibliographic record
Abstract
Background: Oral candidiasis is an opportunistic fungal infection that leads to acute and chronic infections in the mouth and gastrointestinal tract. According to studies, common antifungal drugs have some side effects and sometimes fail in Candida albicans candidiasis infections. Objectives: This study aimed to compare the efficacy of Aloe vera to that of nystatin on oral Candida species in vitro. Methods: This laboratory study was prepared in vitro from a collection of fungi and bacteria in Iran. The measured inhibitory concentration was within the range of 1:1 to 1:2048. The data were analyzed using SPSS software (version 24). Results: In C. albicans species, the inhibitory concentration of Aloe vera gel was 312.5 μL/mL. The inhibitory concentrations for Candida glabrata and Candida tropicalis were 1250 and 625 μL/mL, respectively. In all groups, there was a significant relationship between Aloe vera and nystatin. Conclusions: Aloe vera gel showed antifungal properties in all tested species. The inhibitory concentrations of Aloe vera were much higher than nystatin. Therefore, to use this plant for humans, the concentration of its toxicity to humans should be estimated beforehand to avoid possible harm.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.004 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".