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Record W4288701782 · doi:10.1101/2022.07.26.22278041

Urinary tract infection in infants with asymptomatic Jaundice: a meta-analysis UTI and Jaundice Review

2022· preprint· en· W4288701782 on OpenAlexaboutno aff
Anand Gourishankar, Smita Akkinapally

Bibliographic record

VenuemedRxiv · 2022
Typepreprint
Languageen
FieldMedicine
TopicPediatric Urology and Nephrology Studies
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineJaundiceAsymptomaticPublication biasCochrane LibraryIncidence (geometry)Meta-analysisObservational studyUrinary systemPediatricsInternal medicineConfidence intervalFunnel plot

Abstract

fetched live from OpenAlex

Abstract INTRODUCTION Infants, especially neonates, present with jaundice with an unclear association with urinary tract infection. Evidence for such association is unclear, especially in a specific group of otherwise well-appearing infants born > 35 weeks. EVIDENCE ACQUISITION Data sources We used the following databases: Medline, Embase, CINAHL Plus, Scopus, and Cochrane library. Study selection We included observational studies that included infants born > 35 weeks gestation, younger than 12 months, asymptomatic other than jaundice, and urinary tract infection. Data extraction: After reviewing the eligibility, two reviewers extracted data and assessed the quality of each study using the Newcastle-Ottawa scale. EVIDENCE SYNTHESIS We analyzed sixteen studies for a total of 2933 infants. The pooled incidence of UTI was 9.6% (95% confidence interval of 6% to 15%). The subgroup analysis failed to show any difference in incidence within the publication year, sample size, study design, study region, urine collection method, and age group. There was no explanation of heterogeneity noted by the meta-regression for UTI incidence with publication year, total bilirubin, sample size, and study quality. The funnel plot and Egger’s test revealed publication bias. CONCLUSIONS Nearly 1 in 10 otherwise asymptomatic infants with jaundice have a UTI. We recommend a rigorous large prospective study to confirm this finding.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.011
metaresearch head score (Gemma)0.032
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.016
Threshold uncertainty score0.056

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0110.032
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0160.024
Bibliometrics0.0060.007
Science and technology studies0.0010.001
Scholarly communication0.0040.002
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.054
GPT teacher head0.335
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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