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Record W4289711466 · doi:10.1101/2022.08.02.502528

Perception of dynamic facial expressions activates a cortico-subcortico-cerebellar network in marmosets

2022· preprint· en· W4289711466 on OpenAlexafffund
Audrey Dureux, Alessandro Zanini, Stefan Everling

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2022
Typepreprint
Languageen
FieldNeuroscience
TopicFace Recognition and Perception
Canadian institutionsWestern University
FundersNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health ResearchCanada First Research Excellence Fund
KeywordsMarmosetCallithrixPsychologyNeuroscienceAmygdalaFacial expressionPremotor cortexPerceptionFunctional magnetic resonance imagingArousalPrimateCognitive psychologyCommunicationBiologyAnatomy

Abstract

fetched live from OpenAlex

Abstract The perception and identification of faces and facial emotional expressions are critical for social communication in the daily life of all primates. Here, we investigated the neural network activated by dynamic facial expressions in awake New World common marmosets with ultra-high field fMRI at 9.4T. Our results show that dynamic facial expressions activate several areas along the occipitotemporal axis (V2/V3, V4/TEO, FST, caudal TE, rostral TE, TPO), frontal cortex (areas 45/47, 13, 8a and orbital cortex), amygdala, motion-sensitive areas, premotor area, and in the posterior lobe of the cerebellum. Negative faces increased the monkeys’ respiration rates and elicited stronger responses along the occipitotemporal cortical axis, in the amygdala and in the hypothalamus. This cortico-subcortico-cerebellar network may play an important role in the perception of behaviorally relevant facial expressions that are vital for social communication in marmosets. Significance Statement Recent research has highlighted the importance of emotional content of faces in social communication in humans and non-human primates. The current study focuses on the neural responses to dynamic emotional facial expressions in the common marmoset (Callithrix jacchus), a New World primate species sharing several similarities of social behavior with humans. Using ultra-high-field fMRI, we show that negative facial expressions activate a cortico-subcortico-cerebellar network and, critically, negative faces increase the level of arousal of marmosets, possibly relayed through a modulation of the activity in the autonomic nervous system via stress-integrative brain centres in the hypothalamus. Our results reveal the existence of specific neural and physiological responses to negative emotional faces suggesting that behaviorally relevant facial expressions are vital for social communication in New World marmosets.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.260
Teacher spread0.236 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2022
Admission routes2
Has abstractyes

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