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Record W4289827121 · doi:10.1051/radiopro/2022022

Complementary lessons learned from the testing strategies used for radiation emergencies and COVID-19: A white paper from The International Association of Biological and Electron Paramagnetic Resonance (EPR) Radiation Dosimetry (IABERD)

2022· article· en· W4289827121 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueRadioprotection · 2022
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicRadiation Effects and Dosimetry
Canadian institutionsHealth Canada
Fundersnot available
KeywordsBiodosimetryRadiological weaponMedicinePandemicCoronavirus disease 2019 (COVID-19)Medical physicsModalitiesIntensive care medicineDiseasePathologyIonizing radiationRadiologyInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

As COVID-19 emerged, there are parallels between the responses needed for managing SARS-CoV-2 infections and radiation injuries. While some SARS-CoV-2-infected individuals present as asymptomatic, others exhibit a range of symptoms including severe and rapid onset of high-risk indicators of mortality. Similarly, a variety of responses are also observed after a radiological exposure depending on radiation dose, dose heterogeneity, and biological variability. The impact of acute radiation syndrome (ARS) has guided the identification of many biomarkers of radiation exposure, the establishment of medical management strategies, and development of medical countermeasures in the event of a radiation public health emergency. Biodosimetry has a prominent role for identifying exposed persons during a large scale radiological emergency situation. Identifying exposed individuals is also critical in the case of pandemics such as COVID-19, with the additional goal of controlling the spread of disease. Conclusions and significance: IABERD has taken advantage of its competences in biodosimetry to draw lessons from current practices of managing the testing strategy for nuclear accidents to improve responses to SARS-CoV-2. Conversely, lessons learned from managing SARS-CoV-2 can be used to inform best practices in managing radiological situations. Finally, the potential need to deal with testing modalities simultaneously and effectively in both situations is considered.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.595
Threshold uncertainty score0.741

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.053
GPT teacher head0.288
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it