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Record W4289835801 · doi:10.1093/aje/kwac137

Causal and Associational Language in Observational Health Research: A Systematic Evaluation

2022· article· en· W4289835801 on OpenAlex
Noah Haber, Sarah Wieten, Julia M. Rohrer, Onyebuchi A. Arah, Peter W. G. Tennant, Elizabeth A. Stuart, Eleanor J. Murray, Sophie Pilleron, Sze Tung Lam, Emily Riederer, Sarah J. Howcutt, Alison E. Simmons, Clémence Leyrat, Philipp Schoenegger, Anna Booman, Mi‐Suk Kang Dufour, Ashley L. O’Donoghue, Rebekah Baglini, Stefanie Do, Mari Takashima, Thomas Rhys Evans, Daloha Rodríguez-Molina, Taym Alsalti, Daniel J. Dunleavy, Gideon Meyerowitz‐Katz, Alberto Antonietti, Jose Andrés Calvache, Mark Kelson, Meg G. Salvia, Camila Olarte Parra, Saman Khalatbari‐Soltani, Taylor McLinden, Arthur Chatton, Jessie Seiler, Andreea Steriu, Talal S. Alshihayb, Sarah E. Twardowski, Julia Dabravolskaj, Eric Au, Rachel A. Hoopsick, Shashank Suresh, Nicholas Judd, Sebastián Peña, Cathrine Axfors, Palwasha Khan, Ariadne Rivera‐Aguirre, Nnaemeka U. Odo, Ian Schmid, Matthew P. Fox

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAmerican Journal of Epidemiology · 2022
Typearticle
Languageen
FieldMathematics
TopicAdvanced Causal Inference Techniques
Canadian institutionsUniversity of AlbertaMcGill UniversityAIDS VancouverUniversity of Toronto
FundersNational Center for Advancing Translational SciencesNational Institute of Biomedical Imaging and BioengineeringNational Institute of Mental HealthMedical Research CouncilNational Institutes of HealthLaura and John Arnold FoundationArnold VenturesStanford UniversityBloomberg American Health Initiative
KeywordsObservational studyMedicineLinguisticsPsychologyPathologyPhilosophy

Abstract

fetched live from OpenAlex

We estimated the degree to which language used in the high-profile medical/public health/epidemiology literature implied causality using language linking exposures to outcomes and action recommendations; examined disconnects between language and recommendations; identified the most common linking phrases; and estimated how strongly linking phrases imply causality. We searched for and screened 1,170 articles from 18 high-profile journals (65 per journal) published from 2010-2019. Based on written framing and systematic guidance, 3 reviewers rated the degree of causality implied in abstracts and full text for exposure/outcome linking language and action recommendations. Reviewers rated the causal implication of exposure/outcome linking language as none (no causal implication) in 13.8%, weak in 34.2%, moderate in 33.2%, and strong in 18.7% of abstracts. The implied causality of action recommendations was higher than the implied causality of linking sentences for 44.5% or commensurate for 40.3% of articles. The most common linking word in abstracts was "associate" (45.7%). Reviewers' ratings of linking word roots were highly heterogeneous; over half of reviewers rated "association" as having at least some causal implication. This research undercuts the assumption that avoiding "causal" words leads to clarity of interpretation in medical research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.058
metaresearch head score (Gemma)0.053
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.164
Threshold uncertainty score0.970

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0580.053
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.676
GPT teacher head0.598
Teacher spread0.079 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it