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Peer Review #3 of "Randomized feasibility trial of the Scleroderma Patient-centered Intervention Network hand exercise program (SPIN-HAND) (v0.2)"

2022· peer-review· en· W4292356741 on OpenAlexafffund

Bibliographic record

Venuenot available
Typepeer-review
Languageen
FieldMedicine
TopicSystemic Sclerosis and Related Diseases
Canadian institutionsMcGill University Health CentreSt Joseph's Health CareMultiple Sclerosis Society of CanadaMcGill UniversityJewish General Hospital
FundersLady Davis Institute for Medical ResearchCanadian Institutes of Health ResearchScleroderma Society of OntarioJewish General HospitalArthritis SocietyFondation de l'Hôpital général juifMcGill University
KeywordsRandomized controlled trialPhysical therapyIntervention (counseling)MedicinePhysical medicine and rehabilitationSurgeryNursing

Abstract

fetched live from OpenAlex

enrollment, cohort participants consent to be assessed for trial eligibility and randomized prior to being informed about trials conducted using the cohort.When trials are conducted in the cohort, participants randomized to the intervention are informed and must consent to access the intervention.Participants randomized to control are not informed that they have not received an intervention.All participants eligible and randomized to participate in the trial are included in analyses on an intent-to-treat basis.Cohort participants with a Cochin Hand Function Scale score ≥ 3/90 and an interest in using an online hand-exercise intervention were randomized (1:1 ratio) to be offered usual care plus the SPIN-HAND Program or usual care for 3 months.User satisfaction was assessed with semi-structured interviews.Results: Of 40 participants randomized: 24 were allocated to SPIN-HAND and 16 to usual care.Of 24 participants randomized to be offered SPIN-HAND, 15 (63%) consented to use the program.Usage of SPIN-HAND content among the 15 participants who consented to use the program was low; only 5 (33%) logged in more than twice.Participants found the content relevant and easy to understand (satisfaction rating 8.5/10, N=6).Automated eligibility and randomization procedures via the SPIN Cohort platform functioned properly.Required technical support was minimal.Conclusions: Trial methodology functioned as designed, and the SPIN-HAND Program was feasibly delivered, but acceptance of the offer and use of program content among accepters were low.Adjustments to information provided to potential participants will be implemented in the full-scale SPIN-HAND trial to attempt to increase offer acceptance.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.040
metaresearch head score (Gemma)0.193
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: Evaluation · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.960
Threshold uncertainty score0.755

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0400.193
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0040.002
Bibliometrics0.0020.002
Science and technology studies0.0050.002
Scholarly communication0.0080.003
Open science0.0050.004
Research integrity0.0060.003
Insufficient payload (model declined to judge)0.4710.166

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.356
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainEvaluation
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2022
Admission routes2
Has abstractyes

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