Cognitive Function and Vitamin D Status in the Chinese Hemodialysis Patients
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Post-publication record
- Nature
- Retraction
- Reason
- Compromised Peer Review;Investigation by Journal/Publisher;Investigation by Third Party;Paper Mill;Unreliable Results and/or Conclusions;
- Date
- 12/6/2023 0:00
- Flagged by OpenAlex?
- Yes
Source: Retraction Watch, joined by DOI. OpenAlex records retraction as is_retracted, a boolean over a state space with at least four values, so it cannot express an expression of concern, a correction or a reinstatement — it reports them as false, which reads as “fine”.
Abstract
Objective. Vitamin D insufficiency and the cognitive function decline are both common in patients receiving hemodialysis (HD). The present study evaluated the relation between cognitive function and circulating vitamin D levels in HD patients in Wannan Medical College Affiliated Yijishan Hospital, China. Methods. This study was conducted in 80 patients receiving HD in Wannan Medical College Affiliated Yijishan Hospital. To measure cognitive function, Montreal Cognitive Assessment-Basic (MoCA-B) Chinese Version was used. The 25-hydroxyvitamin D [25(OH)D], which is applied to assess vitamin D status, was tested. One-way ANOVA, Tukey post hoc test, and the correlation and regression analysis were used in this study. Results. Based on the MoCA-B, cognitive function decline (the scores below 26) was present in 28 HD patients, accounting for 35% (28/80). The mean age of these patients is <a:math xmlns:a="http://www.w3.org/1998/Math/MathML" id="M1"> <a:mn>50.5</a:mn> <a:mo>±</a:mo> <a:mn>10.9</a:mn> </a:math> years old. The mean level of 25(OH)D was <c:math xmlns:c="http://www.w3.org/1998/Math/MathML" id="M2"> <c:mn>16.1</c:mn> <c:mo>±</c:mo> <c:mn>7.3</c:mn> <c:mtext> </c:mtext> <c:mtext>ng</c:mtext> <c:mo>/</c:mo> <c:mtext>ml</c:mtext> </c:math> in 80 HD patients. In univariate analysis, there was a significant relationship between MoCA-B score and serum 25(OH)D level ( <e:math xmlns:e="http://www.w3.org/1998/Math/MathML" id="M3"> <e:mi>p</e:mi> <e:mo><</e:mo> <e:mn>0.05</e:mn> </e:math> ). The level of 25(OH)D was positively correlated with MoCA-B score ( <g:math xmlns:g="http://www.w3.org/1998/Math/MathML" id="M4"> <g:mi>r</g:mi> <g:mo>=</g:mo> <g:mn>0.312</g:mn> </g:math> , <i:math xmlns:i="http://www.w3.org/1998/Math/MathML" id="M5"> <i:mi>p</i:mi> <i:mo>=</i:mo> <i:mn>0.023</i:mn> </i:math> ), and the association was independent of demographic and clinical features. Conclusions. Vitamin D insufficiency may contribute to cognitive function decline in HD patients. Serum level of 25(OH)D is an independent protective factor of cognitive function in the HD patients.
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The record
- Venue
- Computational and Mathematical Methods in Medicine
- Topic
- Vitamin D Research Studies
- Field
- Medicine
- Canadian institutions
- —
- Funders
- University Natural Science Research Project of Anhui ProvinceWannan Medical College
- Keywords
- HemodialysisCognitionVitamin D and neurologyVitaminMedicineFunction (biology)PsychologyInternal medicineBiologyPsychiatry
- Has abstract in OpenAlex
- yes