A comparative study of effectiveness of microneedling with and without topical corticosteroids in post-burn hypertrophic scars of face and neck
Bibliographic record
Abstract
Background: The standard treatment of post-burns scars has unsatisfactory outcomes and required several treatments. Objective: To evaluate efficacy of the microneedling with or without topical steroids on treatment of post-burn hypertrophic scars in face and neck. Patients and Methods: We included patients with post-burn hypertrophic scar of face and neck, caused by burn within the 1st year after burn, we excluded patients with coagulation defects. Patients were divided into 3 groups; Group A: microneedling once/month for 5 months, Group B: microneedling with topical steroids once/month for 5 months, and Group C: control group for just conservative treatment. Histopathological study was used for evaluation. Results: we included 60 participants; the mean age was 20 ± 9 years. After 3 & 6 months microneedling significantly decrease the Vancouver scar scale (VSS), and adding steroids significantly improve the results. Microneedling group significantly decreased the VSS after 3 and 6 months. Moreover, adding steroids significantly improved the results. Histopathologicaly, after 6 months, there was statistically difference between the three groups in thickness (p= <0.001), Nodules (p= 0.02) and inflammation (p= 0.02) of the scar. Conclusion: Microneedling with or without topical steroids found to improve the outcomes of post-burn hypertrophic scars.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".