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Record W4296236316 · doi:10.21203/rs.3.rs-1963931/v1

Pre-calving energy density and rumen protected lysine impacted blood metabolites and biomarkers of liver functions in dairy cows during the transition period.

2022· preprint· en· W4296236316 on OpenAlexfundno aff
Girma Debele Delelesse, Lu Ma, Fang Wang, Toddy Callaway, Dengpan Bu

Bibliographic record

VenueResearch Square · 2022
Typepreprint
Languageen
FieldAgricultural and Biological Sciences
TopicReproductive Physiology in Livestock
Canadian institutionsnot available
FundersAgricultural Science and Technology Innovation ProgramNational Key Research and Development Program of ChinaChinese Academy of Agricultural SciencesUniversity of Manitoba
KeywordsIce calvingRumenAlbuminLysineAnimal scienceEnergy balanceChemistryLactationInternal medicineLiver functionEndocrinologyBiologyBiochemistryFermentationMedicineAmino acidPregnancy

Abstract

fetched live from OpenAlex

Abstract Dairy cow usual faces negative energy balance and disorder of normal organs function due to mismatch between energy intake and energy demands. Negative energy balance directly affects liver function and blood metabolites because of liver used as source of energy supply and center of metabolic activity. The study aimed to determine the effect of pre-calving energy density and rumen-protected lysine on blood metabolites and biomarkers of liver functions in dairy cows during the transition period. Forty 3rd lactation Holstein cows were randomly allocated to one of the four dietary treatments (High energy with rumen-protected lysine (HERPL) = 1.53NEL plus 40 g Lys, High energy without lysine (HECK) = 1.53NEL, Low energy with rumen-protected lysine (LERPL) = 1.37NEL plus 40 g Lys, and Low energy without lysine (LECK) = 1.37NEL arranged in a 2 x 2 factorial design. Blood samples were collected during the transition period and concentrations of blood metabolites and biomarkers of liver functions were measured. Interaction between pre-calving high energy diet and RPL tended to increase plasma albumin, numerically increased glucose, decreased TG, total bilirubin and AST concentrations. The result revealed that pre-calving high energy diet increased insulin, albumin and decreased blood urea nitrogen and total bilirubin concentrations and substantial favor liver functions during the transition period.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.283
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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