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Record W4296620240 · doi:10.1093/jas/skac247.107

117 Assessment of Complete Blood Count and Biochemistry Parameters in Adult Dogs fed a Grain-Free Diet with up to Forty-Five Percent Pulse Inclusion

2022· article· en· W4296620240 on OpenAlexaff
Pawanpreet Singh, Sydney Banton, James R Templeman, Shari Raheb, Jennifer Saunders-Blades, Darcia Kostiuk, Janelle Kelly, Adronie Verbrugghe, Anna‐Kate Shoveller

Bibliographic record

VenueJournal of Animal Science · 2022
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPeroxisome Proliferator-Activated Receptors
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsMealAnimal scienceMicronutrientBody weightMedicineHemoglobinBiologyInternal medicinePathology

Abstract

fetched live from OpenAlex

Abstract With interest in grain-free diets (GFD) and plant-based diets, understanding the use of pulse ingredients is warranted. Recently our laboratory found that high pulse inclusive diets did not cause echocardiographic changes in healthy adult dogs after 20 weeks of feeding. Thus, the objective of this study was to assess the safety of pulse ingredient inclusion up to 45% in canine diets using gross physiological, hematological and biochemical measurements. Twenty-eight healthy adult Siberian huskies were fed one of four experimental diets formulated to achieve the same macronutrient targets and the same micronutrient supplementation for 20 weeks: 1) grain-inclusive diet, with 45% corn, 0% pulses (Control); 2) GFD, 15% pulses (Pulse15); 3) GFD, 30% pulses (Pulse30) 4) GFD, 45% pulses (Pulse45). All diets included chicken meal and the same combination of pulse ingredients; green and yellow peas, pinto beans, chickpeas, and lentils. Dogs were fed once daily. Body weight was measured weekly, feed intake measured daily, and body composition was measured using DEXA at baseline and week 20. Fasted blood samples were collected at weeks -3, 3, 6, 10, 14 and 18. Data were analyzed as repeated measures in SAS using PROC GLIMMIX. Body weight, body composition, and feed intake were similar among treatments and over time (P >0.05). Several blood parameters were different among treatments but remained within defined reference ranges for healthy dogs. Red blood cells, hemoglobin and carbon dioxide were greater, while lymphocytes were reduced in Pulse45 than Pulse15 (P< 0.05), but similar to Control and Pulse30. Mean corpuscular hemoglobin concentration was decreased in Control and Pulse15 compared with Pulse30 and Pulse45 (P< 0.05). Gamma-glutamyl transferase was less in Control and Pulse15 than Pulse45 (P< 0.05), but similar to Pulse30. These data suggest that feeding diets with up to 45% pulse inclusion for 20 weeks does not impact gross health parameters of healthy adult dogs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.267
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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