PSIII-A-3 An Investigation of the Effect of Folic Acid and its Delivery Routes on Broiler Chickens’ Hatch and Growth Performance, Blood Biochemistry, and Antioxidant Status
Bibliographic record
Abstract
Abstract This study investigated the effect of folic acid (FA) and its delivery routes (in-feed or in ovo) on broiler chicken’s hatch and growth performance, blood biochemistry, and antioxidant status. A total of 1,860 Cobb 500 hatching eggs were incubated for 21 days. On d 12 of incubation, viable eggs were randomly allotted to 3 groups: the non-injected group, in ovo folic acid 1 (FA1), and in ovo folic acid 2 groups (FA2) and subsequently injected with 0.1 ml FA containing 0.1 mg and 0.15 mg/egg, via the amnion, respectively. At hatch, chicks were re-allotted to 5 new treatment groups: FA1, FA2, in-feed folic acid (FA3; 5mg/kg), in-feed bacitracin methylene disalicylate (BMD; 55 mg/kg), and negative control (NC; corn-wheat-soybean diet) in 6 replicate pens (22 birds/pen) and raised in starter (d 0 -14), grower (d 15-24) and finisher (d 25-35) phases. Hatch parameters were assessed on d 0, and body weight and feed intake (FI) were determined weekly. On d 25, 1 bird/cage was euthanized, and immune organs weighed. Blood samples were collected for biochemistry and antioxidant (Superoxide dismutase-SOD and Malondialdehyde-MDA) analysis. Data were analyzed in a randomized complete block design. While FA1 and FA2 decreased (P< 0.001) hatchability in a dose-dependent manner, FA2 caused a 2% increase (P< 0.05) in average chick weight compared to the non-injected group. Compared to the BMD treatment, FA3 decreased (P< 0.05) average FI across all feeding phases. However, only in the grower phase did BMD treatment record a lower (P< 0.05) feed conversion ratio (FCR) compared to the NC treatment. Other treatments recorded intermediate FCR values. FA1 and FA2 recorded a tendency (P< 0.1) to increase MDA levels and SOD activity by 50% and 19%, respectively, compared to the NC treatment. Besides its negative effect on hatchability, FA2 may help improve embryonic development and antioxidant status in broiler chickens.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".