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Record W4301396488 · doi:10.5334/dsj-2022-017

A Survey on Publicly Available Open Datasets Derived From Electronic Health Records (EHRs) of Patients with Neuroblastoma

2022· article· en· W4301396488 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueData Science Journal · 2022
Typearticle
Languageen
FieldMedicine
TopicNeuroblastoma Research and Treatments
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsNeuroblastomaComputer scienceHealth recordsOpen scienceLicenseThe InternetElectronic health recordOpen dataWorld Wide WebInternet privacyMedicineInformation retrievalData miningPolitical scienceMathematicsStatisticsHealth care

Abstract

fetched live from OpenAlex

<strong>Background:</strong> Neuroblastoma is a rare pediatric cancer that affects thousands of children worldwide. Information stored in electronic health records can be a useful source of data forin silicoscientific studies about this disease, carried out both by humans and by computational machines. Several open datasets derived from electronic health records of anonymized patients diagnosed with neuroblastoma are available in the internet, but they were released on different websites or as supplementary information of peer-reviewed scientific publications, making them difficult to find. <strong>Methods:</strong> To solve this problem, we present here this survey of five open public datasets derived from electronic health records of patients diagnosed with neuroblastoma, all collected in a single website called Neuroblastoma Electronic Health Records Open Data Repository. <strong>Results:</strong> The five open datasets presented in this survey can be used by researchers worldwide who want to carry on scientific studies on neuroblastoma, including machine learning and computational statistics analyses. <strong>Conclusions:</strong> We believe our survey and our open data resource can have a strong impact in oncology research, allowing new scientific discoveries that can improve our understanding of neuroblastoma and therefore improve the conditions of patients. We release the five open datasets reviewed here publicly and freely on our Neuroblastoma Electronic Health Records Open Data Repository under the CC BY 4.0 license at: <a href="https://davidechicco.github.io/neuroblastoma_EHRs_data" target="_blank">https://davidechicco.github.io/neuroblastoma_EHRs_data</a> or at <a href="https://doi.org/10.5281/zenodo.6915403" target="_blank">https://doi.org/10.5281/zenodo.6915403</a>

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmaOpen science
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Observationallow
gptno category
Domain: not available · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Other designlow
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.277
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.002
Open science0.0030.002
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.073
GPT teacher head0.350
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it