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Record W4303685093 · doi:10.1093/eurheartj/ehac426

CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research

2022· article· en· W4303685093 on OpenAlexfundno aff
Dipak Kotecha, Folkert W. Asselbergs, Stephan Achenbach, Stefan D. Anker, Dan Atar, Colin Baigent, Amitava Banerjee, Birgit Beger, Gunnar Brobert, Barbara Casadei, Cinzia Ceccarelli, Martín Cowie, Filippo Crea, Maureen Cronin, Spiros Denaxas, Andrea Derix, Donna Fitzsimons, Martin Fredriksson, Chris P Gale, Georgios V. Gkoutos, Wim Goettsch, Harry Hemingway, Martin Ingvar, Adrian Jonas, Robert Kazmierski, Susanne Løgstrup, R Thomas Lumbers, Thomas F. Lüscher, Paul McGreavy, Ileana L. Piña, Lothar Roessig, Carl Steinbeisser, Mats Sundgren, Benoît Tyl, Ghislaine J. M. W. van Thiel, Kees van Bochove, Panos Vardas, Tiago Villanueva, Marilena Vrana, Wim Weber, Franz Weidinger, Stephan Windecker, Angela Wood, Diederick E. Grobbee, Xavier Kurz, John Concato, Jose P. Morales, Niklas Hedberg, Stuart Spencer, Rupa Sarkar, Colm Carroll, Ceri Thompson, Valentina Tursini, R Tom Lumbers, Rick Grobbee, Anastasia Petrova, Katija Baljevic, Polyxeni Vairami, Jennifer Taylor

Bibliographic record

VenueEuropean Heart Journal · 2022
Typearticle
Languageen
FieldHealth Professions
TopicElectronic Health Records Systems
Canadian institutionsnot available
FundersMedical Research CouncilRespicardiaAbbott VascularInnovative Medicines InitiativeZorginstituut NederlandCSL BehringNational Institute for Health and Care ResearchSanofiAbiomedMyoKardiaBritish Heart FoundationEuropean Federation of Pharmaceutical Industries and AssociationsRegeneron PharmaceuticalsInfraRedxMedicureAmgenEuropean Society of CardiologyBoston Scientific CorporationAstraZenecaUniversity of OxfordNational Institute for Health and Care ExcellenceCardinal HealthEdwards LifesciencesEuropean CommissionDaiichi Sankyo EuropeServierBayerVifor PharmaPfizer
KeywordsMedicineElectronic health recordHealth recordsCode (set theory)Best practiceHealth careMedical emergencyProgramming language

Abstract

fetched live from OpenAlex

Big data is central to new developments in global clinical science aiming to improve the lives of patients. Technological advances have led to the routine use of structured electronic healthcare records with the potential to address key gaps in clinical evidence. The covid-19 pandemic has demonstrated the potential of big data and related analytics, but also important pitfalls. Verification, validation, and data privacy, as well as the social mandate to undertake research are key challenges. The European Society of Cardiology and the BigData@Heart consortium have brought together a range of international stakeholders, including patient representatives, clinicians, scientists, regulators, journal editors and industry. We propose the CODE-EHR Minimum Standards Framework as a means to improve the design of studies, enhance transparency and develop a roadmap towards more robust and effective utilisation of healthcare data for research purposes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.063
metaresearch head score (Gemma)0.018
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Science and technology studies, Research integrity
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.376
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0630.018
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0040.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.018
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.559
GPT teacher head0.617
Teacher spread0.057 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations36
Published2022
Admission routes1
Has abstractyes

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