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Record W4304098575 · doi:10.1002/mp.16005

3D‐printed large‐area focused grid for scatter reduction in cone‐beam CT

2022· article· en· W4304098575 on OpenAlexafffund
Santiago F. Cobos, Chris J. D. Norley, Hristo N. Nikolov, David W. Holdsworth

Bibliographic record

VenueMedical Physics · 2022
Typearticle
Languageen
FieldMedicine
TopicDigital Radiography and Breast Imaging
Canadian institutionsWestern University
FundersCanadian Institutes of Health Research
KeywordsFlat panel detectorOpticsDetectorCone beam computed tomographyImage qualityMaterials scienceImage sensorBeam (structure)X-ray detectorGridPhysicsComputer scienceArtificial intelligenceGeometryComputed tomographyMedicineMathematics

Abstract

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BACKGROUND: Cone-beam computed tomography (CBCT) systems acquire volumetric data more efficiently than fan-beam or multislice CT, particularly when the anatomy of interest resides within the axial field-of-view of the detector and data can be acquired in one rotation. For such systems, scattered radiation remains a source of image quality degradation leading to increased noise, image artifacts, and CT number inaccuracies. PURPOSE: Recent advances in metal additive manufacturing allow the production of highly focused antiscatter grids (2D-ASGs) that can be used to reduce scatter intensity, while preserving primary radiation transmission. We present the first implementation of a large-area, 2D-ASG for flat-panel CBCT, including grid-line artifact removal and related improvements in image quality. METHODS: A 245 × 194 × 10 mm 2D-ASG was manufactured from chrome-cobalt alloy using laser powder-bed fusion (LPBF) (AM-400; Renishaw plc, New Mills Wotton-under-Edge, UK). The 2D-ASG had a square profile with a pitch of 9.09 lines/cm and 10:1 grid-ratio. The nominal 0.1 mm grid septa were focused to a 732 mm x-ray source to optimize primary x-ray transmission and reduce grid-line shadowing at the detector. Powder-bed fusion ensured the structural stability of the ASG with no need for additional interseptal support. The 2D-ASG was coupled to a 0.139-mm element pitch flat-panel detector (DRX 3543, Carestream Health) and proper alignment was confirmed by consistent grid-line shadow thickness across the whole detector array. A 154-mm diameter CBCT image-quality-assurance phantom was imaged using a rotary stage and a ceiling-mounted, x-ray unit (Proteus XR/a, GE Medical Systems, 80kVp, 0.5mAs). Grid-line artifacts were removed using a combination of exposure-dependent gain correction and spatial-frequency, Fourier filtering. Projections were reconstructed using a Parker-weighted, FDK algorithm and voxels were spatially averaged to 357 × 357 × 595 µm to improve the signal-to-noise characteristics of the CBCT reconstruction. Finally, in order to compare image quality with and without scatter, the phantom was scanned again under the same CBCT conditions but with no 2D-ASG. No additional antiscatter (i.e., air-gap, bowtie filtration) strategies were used to evaluate the effects in image quality caused by the 2D-ASG alone. RESULTS: The large-area, 2D-ASG prototype was successfully designed and manufactured using LPBF. CBCT image-quality improvements using the 2D-ASG included: an overall 14.5% CNR increase across the volume; up to 48.8% CNR increase for low-contrast inserts inside the contrast plate of the QA phantom; and a 65% reduction of cupping artifact in axial profiles of water-filled cross sections of the phantom. Advanced image processing strategies to remove grid line artifacts did not affect the spatial resolution or geometric accuracy of the system. CONCLUSIONS: LPBF can be used to manufacture highly efficient, 2D-focused ASGs that can be easily coupled to clinical, flat-panel detectors. The implementation of ASGs in CBCT leads to reduced scatter-related artifacts, improved CT number accuracy, and enhanced CNR with no increased equivalent dose to the patient. Further improvements to image quality might be achieved with a combination of scatter-correction algorithms and iterative-reconstruction strategies. Finally, clinical applications where other scatter removal strategies are unfeasible might now achieve superior soft-tissue visualization and quantitative capabilities.

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How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.855
Threshold uncertainty score0.471

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.265
Teacher spread0.249 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2022
Admission routes2
Has abstractyes

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