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Record W4304587499 · doi:10.1037/abn0000743

Assessing general versus specific liability for externalizing problems in adolescence: Concurrent and prospective prediction of symptoms of conduct disorder, ADHD, and substance use.

2022· article· en· W4304587499 on OpenAlexaff
Emily R. Perkins, Keanan J. Joyner, Jens Foell, Laura E. Drislane, Sarah J. Brislin, Paul J. Frick, James R. Yancey, Elia F. Soto, Colleen M. Ganley, Pamela K. Keel, Claudio Sica, Herta Flor, Frauke Nees, Tobias Banaschewski, Arun L.W. Bokde, Sylvane Desrivières, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Bernd Ittermann, Jean‐Luc Martinot, Marie‐Laure Paillère Martinot, Éric Artiges, Dimitri Papadopoulos Orfanos, Luise Poustka, Sarah Hohmann, Juliane H. Fröhner, Michael N. Smolka, Henrik Walter, Robert Whelan, Günter Schumann, Christopher J. Patrick

Bibliographic record

VenueJournal of Psychopathology and Clinical Science · 2022
Typearticle
Languageen
FieldMedicine
TopicAttention Deficit Hyperactivity Disorder
Canadian institutionsTrinity College
FundersNational Institute of Biomedical Imaging and BioengineeringNational Institute on Drug AbuseNational Institute on Alcohol Abuse and AlcoholismMedical Research CouncilU.S. ArmyUniversité Paris-SudFédération pour la Recherche sur le CerveauNational Institute of Mental HealthFondation pour la Recherche MédicaleInstitut National de la Santé et de la Recherche MédicaleAgence Nationale de la RechercheMission Interministérielle de Lutte Contre les Drogues et les Conduites AddictivesU.S. Department of DefenseEli Lilly and CompanyScience Foundation IrelandEuropean CommissionUniversity of OxfordKing’s College LondonNational Institutes of HealthFondation de l'Avenir pour la Recherche Médicale AppliquéeDeutsche ForschungsgemeinschaftKing's College LondonFondation de FranceBundesministerium für Bildung und ForschungNational Institute on AgingNational Institute for Health and Care ResearchH. Lundbeck A/SU.S. Department of Veterans Affairs
KeywordsDisinhibitionConduct disorderPsychologyAntisocial personality disorderClinical psychologyPsychopathologySubstance abuseImpulsivityPsychiatryMalingeringPsycINFOPoison controlDevelopmental psychologyInjury preventionMEDLINEMedicine

Abstract

fetched live from OpenAlex

This study explored the generality versus specificity of two trait-liability factors for externalizing problems-disinhibition and callousness-in the concurrent and prospective prediction of symptoms of conduct disorder, attention-deficit/hyperactivity disorder (ADHD), and substance use (i.e., alcohol use disorder and history of illicit substance use). Disinhibition involves an impulsive, unrestrained cognitive-behavioral style; callousness entails a dispositional lack of social-emotional sensitivity. Participants were European adolescents from the multisite IMAGEN project who completed questionnaires and clinical interviews at ages 14 (N = 1,504, Mage = 14.41, 51.13% female) and 16 (N = 1,407, Mage = 16.46, 51.88% female). Disinhibition was related concurrently and prospectively to greater symptoms of conduct disorder, ADHD, and alcohol use disorder; higher scores on a general externalizing factor; and greater likelihood of having tried an illicit substance. Callousness was selectively related to greater conduct disorder symptoms. These findings indicate disinhibition confers broad liability for externalizing spectrum disorders, perhaps due to its affiliated deficits in executive function. In contrast, callousness appears to represent more specific liability for antagonistic (aggressive/exploitative) forms of externalizing, as exemplified by antisocial behavior. Results support the utility of developmental-ontogenetic and hierarchical-dimensional models of psychopathology and have important implications for early assessment of risk for externalizing problems. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.178
GPT teacher head0.451
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2022
Admission routes1
Has abstractyes

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Same venueJournal of Psychopathology and Clinical ScienceSame topicAttention Deficit Hyperactivity DisorderFrench-language works237,207