MétaCan
Menu
Back to cohort
Record W4304587499 · doi:10.1037/abn0000743

Assessing general versus specific liability for externalizing problems in adolescence: Concurrent and prospective prediction of symptoms of conduct disorder, ADHD, and substance use.

2022· article· en· W4304587499 on OpenAlex
Emily R. Perkins, Keanan J. Joyner, Jens Foell, Laura E. Drislane, Sarah J. Brislin, Paul J. Frick, James R. Yancey, Elia F. Soto, Colleen M. Ganley, Pamela K. Keel, Claudio Sica, Herta Flor, Frauke Nees, Tobias Banaschewski, Arun L.W. Bokde, Sylvane Desrivières, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Bernd Ittermann, Jean‐Luc Martinot, Marie‐Laure Paillère Martinot, Éric Artiges, Dimitri Papadopoulos Orfanos, Luise Poustka, Sarah Hohmann, Juliane H. Fröhner, Michael N. Smolka, Henrik Walter, Robert Whelan, Günter Schumann, Christopher J. Patrick

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Psychopathology and Clinical Science · 2022
Typearticle
Languageen
FieldMedicine
TopicAttention Deficit Hyperactivity Disorder
Canadian institutionsTrinity College
FundersNational Institute of Biomedical Imaging and BioengineeringNational Institute on Drug AbuseNational Institute on Alcohol Abuse and AlcoholismMedical Research CouncilU.S. ArmyUniversité Paris-SudFédération pour la Recherche sur le CerveauNational Institute of Mental HealthFondation pour la Recherche MédicaleInstitut National de la Santé et de la Recherche MédicaleAgence Nationale de la RechercheMission Interministérielle de Lutte Contre les Drogues et les Conduites AddictivesU.S. Department of DefenseEli Lilly and CompanyScience Foundation IrelandEuropean CommissionUniversity of OxfordKing’s College LondonNational Institutes of HealthFondation de l'Avenir pour la Recherche Médicale AppliquéeDeutsche ForschungsgemeinschaftKing's College LondonFondation de FranceBundesministerium für Bildung und ForschungNational Institute on AgingNational Institute for Health and Care ResearchH. Lundbeck A/SU.S. Department of Veterans Affairs
KeywordsDisinhibitionConduct disorderPsychologyAntisocial personality disorderClinical psychologyPsychopathologySubstance abuseImpulsivityPsychiatryMalingeringPsycINFOPoison controlDevelopmental psychologyInjury preventionMEDLINEMedicine

Abstract

fetched live from OpenAlex

This study explored the generality versus specificity of two trait-liability factors for externalizing problems-disinhibition and callousness-in the concurrent and prospective prediction of symptoms of conduct disorder, attention-deficit/hyperactivity disorder (ADHD), and substance use (i.e., alcohol use disorder and history of illicit substance use). Disinhibition involves an impulsive, unrestrained cognitive-behavioral style; callousness entails a dispositional lack of social-emotional sensitivity. Participants were European adolescents from the multisite IMAGEN project who completed questionnaires and clinical interviews at ages 14 (N = 1,504, Mage = 14.41, 51.13% female) and 16 (N = 1,407, Mage = 16.46, 51.88% female). Disinhibition was related concurrently and prospectively to greater symptoms of conduct disorder, ADHD, and alcohol use disorder; higher scores on a general externalizing factor; and greater likelihood of having tried an illicit substance. Callousness was selectively related to greater conduct disorder symptoms. These findings indicate disinhibition confers broad liability for externalizing spectrum disorders, perhaps due to its affiliated deficits in executive function. In contrast, callousness appears to represent more specific liability for antagonistic (aggressive/exploitative) forms of externalizing, as exemplified by antisocial behavior. Results support the utility of developmental-ontogenetic and hierarchical-dimensional models of psychopathology and have important implications for early assessment of risk for externalizing problems. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.469

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.178
GPT teacher head0.451
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it