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Record W4306353440 · doi:10.56588/iabcd.v1i2.56

A REVIEW ON HEPATOPROTECTIVE PLANTS AND COMPOUNDS

2022· review· en· W4306353440 on OpenAlexaff
Harsha Motwani, Harshida Gadhavi, Hitesh Solanki, Saumya Patel, Rakesh Rawal

Bibliographic record

VenueInternational Association of Biologicals and Computational Digest · 2022
Typereview
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicDrug-Induced Hepatotoxicity and Protection
Canadian institutionsImpact
Fundersnot available
KeywordsPhytochemistryPhytochemicalDetoxification (alternative medicine)Medicinal plantsTraditional medicinePharmacologyMedicineBiologyBiotechnologyAlternative medicine

Abstract

fetched live from OpenAlex


 
 
 
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 The liver is one of the most significant organs in the body, executing a fundamental role in the regulation of diverse processes, among which the metabolism, secretion, storage, and detoxification of endogenous and exogenous substances are noticeable. Due to these functions, hepatic diseases have become threat to public health, and they remain as major worldwide issue. Despite enormous advances in modern medicine, there are no completely effective drugs that stimulate hepatic function, that offer complete protection of the organ, or that help to regenerate hepatic cells. Thus, it is necessary to identify pharmaceutical alternatives for the treatment of liver diseases, with the aim of these alternatives being more effective and less toxic. The use of many herbs or their extracts for treatment of various ailments has been documented in Ayurvedic medical system. The immense potential of medicinal plants used in traditional systems has been well recognized and documented in recent years. Numerous plants and polyherbal formulations are used for the treatment of liver diseases. Phytotherapeutic approach to modern drug development can provide many invaluable drugs from traditional medicinal plants. Search for pure phytochemicals as drugs is time consuming and expensive. This review article is going to enumerate some plants with hepatoprotective properties and it is going to provide a robust insight into the phytochemistry, medicinal uses and pharmacology of a few hepatoprotective plants and their compounds. Nonetheless, further study on the phytochemistry and mechanism of action of the pure compounds are necessary to fully understand the phytochemical profile and the complex pharmacological effects of this plant.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.992
Threshold uncertainty score0.989

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.215
GPT teacher head0.467
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2022
Admission routes1
Has abstractyes

Explore more

Same venueInternational Association of Biologicals and Computational DigestSame topicDrug-Induced Hepatotoxicity and ProtectionFrench-language works237,207