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Record W4306943901 · doi:10.21203/rs.3.rs-2169469/v1

Neuroendoscopic Surgery versus Stereotactic Aspiration in the treatment of supratentorial intracerebral hemorrhage: a meta-analysis

2022· preprint· en· W4306943901 on OpenAlexaboutno aff
Shuwen Sun, Xin Huang, Xiaobin Fei, Kai Gong, Xinmin Zhou, Heng Gao

Bibliographic record

VenueResearch Square · 2022
Typepreprint
Languageen
FieldMedicine
TopicIntracerebral and Subarachnoid Hemorrhage Research
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineCochrane LibraryMeta-analysisIntracerebral hemorrhageSubgroup analysisHematomaInclusion and exclusion criteriaSurgeryWeb of scienceInternal medicineGlasgow Coma ScalePathology

Abstract

fetched live from OpenAlex

Abstract Background No consensus has been reached on the superiority between Neuroendoscopic Surgery (NS) versus Stereotactic Aspiration (SA) in the treatment of supratentorial intracerebral hemorrhage (ICH). Therefore, this study conducted in-depth analysis and aimed to evaluate the efficacy and safety of NS versus SA for supratentorial ICH. Methods We searched for the all-relevant studies systematically from English databases including PubMed, Embase, Web of Science and the Cochrane Library. Two independent researchers identified and selected these literatures that met the inclusion criteria. Then we evaluated the quality of these studies according to the Cochrane Collaboration’s risk of bias tool and the Newcastle-Ottawa Scale. RevMan 5.4 statistical software was used to conduct this meta-analysis. Results Fifteen studies, including 2600 supratentorial ICH patients, were included in our meta-analysis. The pooled results showed that NS could effectively reduce the postoperative mortality (P < 0.00001) and increase the hematoma evacuation rate (P < 0.00001). However, no significant difference was found between NS and SA in improving the functional prognosis (P = 0.15). In the aspect of hospital stays (P < 0.00001), no enough evidence could support that SA could shorten the hospital stays better than NS. However, SA had more advantages in shortening operation time (P < 0.00001) and reducing intraoperative blood loss (P < 0.00001). In the aspect of complications, NS could have a positive effect on preventing intracranial infection (P = 0.004). In the subgroup analysis, we found that Initial GCS might be a risk factor affecting prognosis and hematoma volume might be an important factor affecting mortality. Conclusion NS might have more advantages than SA in the treatment of supratentorial ICH. However, SA was also an effective alternative for middle-aged and elderly patients. More high-quality studies were needed to verify our conclusions in the future.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.015
metaresearch head score (Gemma)0.023
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.020
Threshold uncertainty score0.077

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0150.023
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0200.056
Bibliometrics0.0060.005
Science and technology studies0.0010.001
Scholarly communication0.0040.002
Open science0.0020.001
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.280
GPT teacher head0.445
Teacher spread0.165 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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