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Record W4306966011 · doi:10.1002/adbi.202200210

Flagellar Propulsion of Sperm Cells Against a Time‐Periodic Interaction Force

2022· article· en· W4306966011 on OpenAlexaff
Zihan Wang, Anke Klingner, Veronika Magdanz, Merijn W. Hoppenreijs, Sarthak Misra, Islam S. M. Khalil

Bibliographic record

VenueAdvanced Biology · 2022
Typearticle
Languageen
FieldPhysics and Astronomy
TopicMicro and Nano Robotics
Canadian institutionsUniversity of Waterloo
FundersChina Scholarship CouncilFundación Bancaria Caixa d'Estalvis i Pensions de BarcelonaEuropean Commission
KeywordsPropulsionSpermAerospace engineeringAeronauticsPhysicsCell biologyBiologyComputer scienceEngineeringGenetics

Abstract

fetched live from OpenAlex

Abstract Sperm cells undergo complex interactions with external environments, such as a solid‐boundary, fluid flow, as well as other cells before arriving at the fertilization site. The interaction with the oviductal epithelium, as a site of sperm storage, is one type of cell‐to‐cell interaction that serves as a selection mechanism. Abnormal sperm cells with poor swimming performance, the major cause of male infertility, are filtered out by this selection mechanism. In this study, collinear bundles, consisting of two sperm cells, generate propulsive thrusts along opposite directions and allow to observe the influence of cell‐to‐cell interaction on flagellar wave‐patterns. The developed elasto‐hydrodynamic model demonstrates that steric and adhesive forces lead to highly symmetrical wave‐pattern and reduce the bending amplitude of the propagating wave. It is measured that the free cells exhibit a mean flagellar curvature of 6.4 ± 3.5 rad mm‐1 and a bending amplitude of 13.8 ± 2.8 rad mm‐1. After forming the collinear bundle, the mean flagellar curvature and bending amplitude are decreased to 1.8 ± 1.1 and 9.6 ± 1.4 rad mm‐1, respectively. This study presents consistent theoretical and experimental results important for understanding the adaptive behavior of sperm cells to the external time‐periodic force encountered during sperm–egg interaction.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.234
Teacher spread0.229 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2022
Admission routes1
Has abstractyes

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