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Efficacy of endovascular treatment for acute ischemic stroke with large core infarction and its influencing factors

2021· article· en· W4307021141 on OpenAlexaboutno aff
Xue Ma, YI Qian, ZHAO Qiuju, LEI Li, Meng Zhang

Bibliographic record

VenueDOAJ (DOAJ: Directory of Open Access Journals) · 2021
Typearticle
Languageen
FieldNeuroscience
TopicNeurological Disorders and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsEndovascular treatmentMedicineIschemic strokeCore (optical fiber)Stroke (engine)Acute strokeInfarctionInternal medicineCardiologyMyocardial infarctionIschemiaSurgeryComputer scienceTissue plasminogen activatorEngineeringAneurysm

Abstract

fetched live from OpenAlex

Objective To investigate the efficacy and influencing factors of early endovascular treatment (EVT) in the patients encountering acute ischemic stroke with large vessel occlusion (AIS-LVO) in the anterior circulation accompanying large core infarction. Methods The clinical data of 31 patients diagnosed as AIS-LVO accompanying large core infarction who underwent EVT in our hospital from January to November 2020 were collected and retrospectively analyzed. Basic information such as age and gender, as well as National Institutes of Health Stroke Scale (NIHSS) score, Alberta Stroke Project Early Computed Tomography (ASPECTS) score, and collateral circulation scores were collected. Postoperative revascularization condition and antiplatelet medication therapy were also recorded. The patients were subsequently divided into good and poor prognosis groups according to the modified Rankin scale (mRS) in 90 d after surgery. The related predictors for good prognosis here explored by multivariate logistic regression analysis. Results Twenty-five cases (80.6%) obtained postoperative revascularization; the incidence of intracranial hemorrhage (ICH) was 41.9%, with 12.9% being symptomatic intracranial hemorrhage (sICH); the good prognosis rate was 32.2% at 90th day after surgery, and the mortality rate was 12.9%. The patients in the good prognosis group had younger age than those in the poor prognosis group (mRS>2) (OR=0.804, 95% CI=0.657~0.983, P=0.034). Conclusion The patients of AIS-LVO accompanying large core infarction can partially benefit from endovascular treatment, and the age of patients is an important factor affecting prognosis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.238
GPT teacher head0.502
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2021
Admission routes1
Has abstractyes

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